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PPAHV

PPAHV ??? ???
?? ??:
175796-50-6
???:
PPAHV
???(??):
PPAHV;PPAHV >99%;Resiniferatoxin Impurity 3;PHORBOL 12-PHENYLACETATE 13-ACETATE 20-HOMOVANILLATE;((1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a(Acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5;[(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9-[phenylacetyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methylesterbenzeneaceticacid;Benzeneacetic acid, 4-hydroxy-3-methoxy-, [(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-5-oxo-9-[(phenylacetyl)oxy]-1H-cyclopropa[3,4]benz[1,2-e]azulen-3-yl]methyl ester
CBNumber:
CB3451988
???:
C39H44O11
??? ??:
688.76
MOL ??:
175796-50-6.mol

PPAHV ??

?? ?
792.4±60.0 °C(Predicted)
??
1.36±0.1 g/cm3(Predicted)
?? ??
Desiccate at -20°C
???
DMSO: ??? ? ??
??? ??
??
??? ??
??? ??
?? ?? (pKa)
9.85±0.20(Predicted)
??
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WGK ?? 3

PPAHV C??? ??, ??, ??

??

PPAHV is non-pungent resiniferatoxin-type phorboid vanilloid and agonist.

???? ??

Non-pungent vanilloid TRPV1 (VR1) receptor agonist (K i = 3.1 μ M) that displays non-cooperative binding. Induces apoptosis via a non-VR1 mechanism in Jurkat cells and causes vasoconstriction in vivo .

PPAHV ?? ?? ? ???

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PPAHV ?? ??

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