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- ???
- 144-145 °C
- ?? ?
- 567.4±50.0 °C(Predicted)
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- 1.373±0.06 g/cm3(Predicted)
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- 2-8°C
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- ???: ???1mg/mL
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- ?? ?? (pKa)
- 7.34±0.20(Predicted)
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- LogP
- 4.350 (est)
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Shikonin has been used:- to enhance the anti-tumor activity of gefitinib on tyrosine kinase receptor epidermal growth factor receptor (EGFR) in wild-type lung cancer cells
- as an inhibitor of renal aerobic glycosis and a potential
- as an anti-inflammatory agent to test its role to improve lipopolysaccharide (LPS)-induced cardiac dysfunction
- to stimulate bone marrow-derived macrophages (BMDMs) to test the effect of Interferon regulatory factor 1 on cell death
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Shikonin is a major phytochemical compound extracted from the roots of Lithospermum erythrorhizon. It is a natural anthraquinone derivative.Biochem/physiol Actions
Shikonin is a potent anti-fungal agent against C. albicans biofilms. It displays anti-oxidant and chemotherapeutic properties on human glioma cells.??? ?? ?? ? ???
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