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9013-72-3
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HEMOCYANIN, KEYHOLE LIMPET
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KLH;HEMOCYANIN;haemocyanin;HeMocyanins;blue carrier;HEMOCYANIN-HG;Keyhole limpet;BLUE CARRIER(R);HEMOCYANIN TYPE VIII;KLH, BES/Mg2+ Buffer
CBNumber:
CB2327970
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0
MOL ??:
Mol file

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2-8°C
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H2O: ???
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PBS ???
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Off-white to gray
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Megathura crenulata
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H2O: soluble

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WGK ?? 1
F ?????? 10-21

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Hemocyanin from Limulus polyphemus hemolymph has been used:
  • in electrophoretic field gradient focusing as a reference standard for optimizing fluorescence quenching for noncolored proteins
  • as standard protein for pH based crystallization screening experiments
  • in peptide conjugation studies

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Gastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.

Biochem/physiol Actions

The largest hemocyanin molecules consisting of 48 (8 × 6) subunits are present in horseshoe crabs (Limulus polyphemus) have up to eight distinct subunits type (6 × subunit type I, 8 × II, 2 × IIA, 8 × IIIA, 8 × IIIB, 8 × IV, 4 × V, 4 × VI).

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