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4-???-N-(2,4,6-??????)???????

4-???-N-(2,4,6-??????)???????
4-???-N-(2,4,6-??????)??????? ??? ???
?? ??:
349085-82-1
???:
4-???-N-(2,4,6-??????)???????
???(??):
4-???-N-(2,4,6-??????)???????
???:
4-Methoxy-N-(2,4,6-triMethylphenyl)benzenesulfonaMide, 97%
???(??):
CS-2460;SK 137647;GSK137647;GSK137647A;GSK137647A, >98%;GSK137647A, 10 mM in DMSO;FFA4 (GPR120) agonist GS137647A;FFA4 (GPR120) agonist GSK137647A;Benzenesulfonamide, 4-methoxy-N-(2,4,6-trimethylphenyl)-;GSK137647A;GSK-137647A;GSK 137647A;GSK-137647;GSK 137647
CBNumber:
CB22635143
???:
C16H19NO3S
??? ??:
305.39
MOL ??:
349085-82-1.mol
MSDS ??:
SDS

4-???-N-(2,4,6-??????)??????? ??

?? ?
438.1±55.0 °C(Predicted)
??
1.214±0.06 g/cm3(Predicted)
?? ??
2-8°C
???
DMSO??? 100mM, ?????? 50mM?? ?????.
??? ??
??
?? ?? (pKa)
9.23±0.10(Predicted)
??
???? ????
???
??? ?? ?????? 2? ?? ??????. DMSO ?? ??? ??? -20°?? ?? 1?? ?? ??? ? ????.
CAS ??????
349085-82-1
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
0
2 0

4-???-N-(2,4,6-??????)??????? C??? ??, ??, ??

??

4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide is involved in long-chain fatty acid stimulated GLP-1 secretion and has been implicated in glucose homeostasis, adiposity, and regulation of the anti-inflammatory response. It enhances glucose-stimulated insulin secretion in MIN6 cells. It induces intracellular calcium accumulation in U2OS cells; this activity is inhibited by AH 7614.

4-???-N-(2,4,6-??????)??????? ?? ?? ? ???

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?? ??


4-???-N-(2,4,6-??????)??????? ?? ??

???( 114)?? ??
??? ?? ??? ?? ?? ? ??
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4-???-N-(2,4,6-??????)??????? ?? ??:

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