????????
???????? ??
???
171-173 °C(lit.)
?? ?
231.2±23.0 °C(Predicted)
??
1.301 (estimate)
???
1.5605 (estimate)
?? ??
Sealed in dry,Room Temperature
?? ?? (pKa)
11.89±0.70(Predicted)
??? ??
??? ?? ?? ??
??
???? ?????
??????(pH)
8.87 at 24.1℃ and 10g/L
???
7g/100mL(20℃)
BRN
1756620
InChIKey
OKGXJRGLYVRVNE-UHFFFAOYSA-N
LogP
1.8 at 30℃ and pH7.86
CAS ??????
2114-02-5(CAS DataBase Reference)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
??? ??
Xi,Xn
?? ???? ??
36/37/38-20/21/22
?????
26-37/39-24/25-23
????(UN No.)
2811
WGK ??
3
RTECS ??
YR8250000
????
III
HS ??
29309090
??
mouse,LD50,intraperitoneal,1440mg/kg (1440mg/kg),Pharmaceutical Chemistry Journal Vol. 30, Pg. 181, 1996.
???? ??
KE-05-0115
????(GHS):
?? ?:
Warning
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H315
??? ??? ???
????? ?? ?????
?? 2
??
P264, P280, P302+P352, P321,P332+P313, P362
H319
?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
H335
?? ???? ??? ? ??
?? ???? ?? - 1? ??;???? ??
?? 3
??
??????:
P261
??·?·??·???·??·...·????? ??? ????.
P264
?? ??? ?? ??? ????.
P264
?? ??? ?? ??? ????.
P271
?? ?? ??? ? ?? ???? ?????.
P280
????/???/???/?????? ?????.
P302+P352
??? ??? ??? ?? ????.
P305+P351+P338
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
???????? C??? ??, ??, ??
??? ??
white to off-white crystals or crystalline powder
??
2-Imino-4-thiobiuret is used in the design and synthesis of guanylthiourea derivatives which are potential inhibitors of plasmodium falciparum dihydrofolate reductase enzyme. 2-Imino-4-thiobiuret is also used as a reagent in recyclization reactions of N-arylmaleimides with polynucleophilic compounds.
???????? ?? ?? ? ???
???
?? ??
???????? ?? ??
???( 313)?? ??
Americas 1
Belgium 2
China 239
Europe 2
Germany 3
India 20
Japan 4
Slovakia 1
South Korea 1
Switzerland 2
United Kingdom 11
United States 27
Global 313
???????? ?? ??:
N,N'-??????? ???????? ???????? ??????? N,N'-??????? ???????? ??????? ?? ????????
N-METHYLTHIOUREA
1-PHENYL-2-THIOUREA
N,N'-DIISOPROPYLTHIOUREA
1-PHENYL-3-GUANYLTHIOUREA,1-PHENYL-3-GUANYLTHIOUREA 98+%
5-AMINO-2-PHENYL-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE
N-(4-OXO-3,4,5,6,7,8-HEXAHYDRO-2-QUINAZOLINYL)THIOUREA
usafb-45
1-ETHYL-3-GUANYLTHIOUREA HYDROCHLORIDE
THIOUREA