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??????? ??
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- 209-212°
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- 587.8±50.0 °C(Predicted)
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- 1.330±0.06 g/cm3(Predicted)
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- 2-8°C(protect from light)
- ???
- ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic
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- ?? ?? (pKa)
- 5.46±0.10(Predicted)
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- Light yellow to yellow
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| HS ?? | 2933399990 |
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Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.??
ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.??????? ?? ?? ? ???
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Pyridine, 4-(bromomethyl)- (9CI)
4-(?????)???
1-???-4-(4-??????)????
4-(4-?????)-1(2H)-?????
3-HYDROXY-2-PYRIDIN-4-YL-INDEN-1-ONE
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1-Chloro-4-iodobenzene
4-Chlorobenzenamine hydrochloride
1,2-??????????
P-??????
4-Bromochlorobenzene
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