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2-Amino-5-fluorobenzoic acid

2-Amino-5-fluorobenzoic acid ??? ???
?? ??:
446-08-2
???:
2-Amino-5-fluorobenzoic acid
???(??):
5-FLUOROANTHRANILIC ACID;5-FAA;NSC 513308;AURORA KA-5382;BUTTPARK 19\04-54;RARECHEM AL BO 2236;5-Fluoranthranilsure;5-fluoroanthranilicaci;Zavegepant Impurity 74;2-Amino-5-fluorobenzoic
CBNumber:
CB2136554
???:
C7H6FNO2
??? ??:
155.13
MOL ??:
446-08-2.mol
MSDS ??:
SDS

2-Amino-5-fluorobenzoic acid ??

???
181-183 °C(lit.)
?? ?
223.67°C (rough estimate)
??
1.3021 (estimate)
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
1.86±0.10(Predicted)
??? ??
?? ??? ??
??
?? ????? ?? ????
BRN
2803664
InChI
InChI=1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
InChIKey
FPQMGQZTBWIHDN-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=CC(F)=CC=C1N
CAS ??????
446-08-2(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,T
?? ???? ?? 36/37/38
????? 26-36-37/39
WGK ?? 3
?? ?? IRRITANT
HS ?? 29224999
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

2-Amino-5-fluorobenzoic acid MSDS


5-Fluoroanthranilic acid

2-Amino-5-fluorobenzoic acid C??? ??, ??, ??

??? ??

white to light yellow crystal powder

??

2-Amino-5-fluorobenzoic acid is used for the counterselection of TRP1, a commonly used genetic marker in the yeast Saccharoyces Cerevisiae. An antimetabolite for the tryptophan pathway in yeast, and is toxic by virtue of its antimetabolite conversion to 5-Fluorotryptophan. It can be used for the selection of tryptophan auxotroophs.

??

ChEBI: An aminobenzoic acid that is anthranilic acid in which the hydrogen at position 5 on the phenyl ring is replaced by fluorine.

2-Amino-5-fluorobenzoic acid ?? ?? ? ???

???

?? ??


2-Amino-5-fluorobenzoic acid ?? ??

???( 448)?? ??
??? ?? ??? ?? ?? ? ??
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2-Amino-5-fluorobenzoic acid ?? ??:

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