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6-????????

6-????????
6-???????? ??? ???
?? ??:
4250-77-5
???:
6-????????
???(??):
6-????????
???:
6-HYDROXYFLAVANONE
???(??):
6-OH Flavanone;6-HYDROXYFLAVANONE;6'-HYDROXYFLAVANONE;HYDROXYFLAVANONE, 6-;6-Hydroxyflavanone>6-Hydroxyflavanone 99%;6-Hydroxyflavanone,98+%;HYDROXYFLAVANONE, 6-(RG);6-Hydroxyflavanone, ≥ 98.0%;6-hydroxy-2-phenylchroMan-4-one
CBNumber:
CB1709715
???:
C15H12O3
??? ??:
240.25
MOL ??:
4250-77-5.mol
MSDS ??:
SDS

6-???????? ??

???
220-222 °C (dec.) (lit.)
?? ?
464.3±45.0 °C(Predicted)
??
1.288±0.06 g/cm3(Predicted)
?? ?? (pKa)
9.53±0.40(Predicted)
??? ??
powder to crystal
??
White to Orange to Green
BRN
87354
LogP
2.955 (est)
CAS ??????
4250-77-5(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
HS ?? 29329900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

6-???????? C??? ??, ??, ??

??? ??

Slightly yellow-cream powder

??

6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells.

??

ChEBI: A monohydroxyflavanone that is flavanone substituted by a hydroxy group at position 6.

?? ??

6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enanti-omers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis.

6-???????? ?? ?? ? ???

???

?? ??


6-???????? ?? ??

???( 119)?? ??
??? ?? ??? ?? ?? ? ??
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6-???????? ?? ??:

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