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Fmoc-L-tert-leucine

Fmoc-L-tert-leucine ??? ???
?? ??:
132684-60-7
???:
Fmoc-L-tert-leucine
???(??):
FMOC-TLE-OH;(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-3,3-diMethylbutanoic acid;FMOC-TBU-GLY-OH;FMOC-L-TLE-OH;FMOC-TBU-GLYCINE;FMOC-L-T-LEUCINE;RARECHEM EM WB 0083;FMOC-L-TERT-LEUCINE;FMOC-L-T-BUTYLGLYCINE;N-Fmoc-L-tert-leucine
CBNumber:
CB1386464
???:
C21H23NO4
??? ??:
353.41
MOL ??:
132684-60-7.mol
MSDS ??:
SDS

Fmoc-L-tert-leucine ??

???
124-127 °C
?? ?
554.1±33.0 °C(Predicted)
??
1.209±0.06 g/cm3(Predicted)
?? ??
2-8°C
???
≥ 35.3mg/mL in DMSO, ≥ 49.6 mg/mL in EtOH
??? ??
powder to crystal
?? ?? (pKa)
3.92±0.10(Predicted)
??
???? ?? ???
BRN
6662856
CAS ??????
132684-60-7(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????? 22-24/25
WGK ?? 3
?? ?? IRRITANT
HS ?? 29242990
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

Fmoc-L-tert-leucine C??? ??, ??, ??

??? ??

solid

??

Fmoc-Tle-OH is a versatile reactant used in the discovery of potent antagonists of antiapoptotic protein X-linked inhibitor of apoptosis (XIAP) for treatment of cancer. It is also used as reactant in the preparation of phosphino dipeptide derivatices as ligand in copper-phosphine catalyst for asymmetric conjugate addition of alkylzinc reagents to unsaturated ketones.

Fmoc-L-tert-leucine ?? ?? ? ???

???

?? ??


Fmoc-L-tert-leucine ?? ??

???( 195)?? ??
??? ?? ??? ?? ?? ? ??
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Fmoc-L-tert-leucine ?? ??:

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