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?? ???? >9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione
9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione
9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione ??? ???
?? ??:
1174289-18-9
???:
9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione
???(??):
Doxofylline N9-Isomer;Doxofylline Impurity 3;Theophylline Impurity 4;Theophylline impurities824;ZIERWCODDLABQQ-UHFFFAOYSA-N;4.36g（ZZ180902,HPLC 99%)+0.12g+12.56g（190729-2）;Theophylline Impurity 4 (Doxofylline Impurity 3);Doxofylline Impurity 3 (Theophylline Impurity 4);9-((1,3-dioxolan-2-yl)methyl)-1,3-dimethyl-1H-purine-2,6(3H,9H)-dione;Doxofy1ine Inpurity 3 (Theophylline Impurity 4) (Doxofylline Impurity 3)
CBNumber:
CB12695609
???:
C11H14N4O4
??? ??:
266.25
MOL ??:
1174289-18-9.mol
9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione ??
?? ?
505.2±53.0 °C(Predicted)
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1.59±0.1 g/cm3(Predicted)
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Refrigerator
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DMSO(?? ???), ???(?? ???)
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?? ?? (pKa)
0.61±0.70(Predicted)
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9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione C??? ??, ??, ??
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9-(1,3-Dioxolan-2-ylmethyl)-3,9-dihydro-1,3-dimethyl-1H-purine-2,6-dione is an isomer impurity in the synthesis of Doxofylline (D557100), a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases.
9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione ?? ?? ? ???
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9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione ?? ??
???( 69)?? ??
China 63
India 4
United States 2
Global 69
9-(1,3-Dioxolan-2-ylMethyl)-3,9-dihydro-1,3-diMethyl-1H-purine-2,6-dione ?? ??:
