2'-O-(5'-???-β-D-??????)?????
2'-O-(5'-???-β-D-??????)????? ??
- ???
- 80-82°C
- ??
- 1.57±0.1 g/cm3(Predicted)
- ?? ??
- -20°C Freezer
- ???
- ?????(?? ???), DMSO(?? ???), ???(?? ???)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 5.38±0.40(Predicted)
- ??
- ???? ?? ?????
- ???
- ???
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
????? |
24/25 |
|
|
HS ?? |
29321900 |
|
|
????(GHS): |
|
?? ?: |
Danger |
??·?? ??: |
?? |
??·?? ?? |
?? ?? |
?? |
?? ? |
?? ?? |
P- ?? |
H315 |
??? ??? ??? |
????? ?? ????? |
?? 2 |
?? |
|
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
?? ?? ??? ??? |
?? ? ?? ?? ??? ?? |
?? 2A |
?? |
|
P264, P280, P305+P351+P338,P337+P313P |
H350 |
?? ??? ? ?? (????? ?? ???? ???? ???? ??? ?? ????? ??? ???? ??) |
??? ?? |
?? 1A, 1B |
?? |
|
|
H360 |
?? ?? ????? ??? ??? ? ?? |
???? ?? |
?? 1A, 1B |
?? |
|
|
H400 |
????? ?? ??? |
?? ????? ?? - ?? |
?? 1 |
?? |
|
P273, P391, P501 |
H410 |
??? ??? ?? ????? ?? ??? |
?? ????? ?? - ?? |
?? 1 |
?? |
|
P273, P391, P501 |
|
??????: |
P264 |
?? ??? ?? ??? ????. |
P264 |
?? ??? ?? ??? ????. |
P273 |
???? ???? ???. |
P280 |
????/???/???/?????? ?????. |
P302+P352 |
??? ??? ??? ?? ????. |
P305+P351+P338 |
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????. |
P321 |
(…) ??? ???. |
P332+P313 |
?? ??? ??? ???? ??· ??? ????. |
P362 |
??? ??? ?? ?? ?? ????? |
P391 |
???? ????. |
P501 |
...? ??? / ??? ?? ???. |
|
2'-O-(5'-???-β-D-??????)????? C??? ??, ??, ??
??? ??
White to Off-White Solid
2'-O-(5'-???-β-D-??????)????? ?? ?? ? ???
???
?? ??
2'-O-(5'-???-β-D-??????)????? ?? ??
???( 64)?? ??
2'-O-(5'-???-β-D-??????)????? ?? ??:
Doxifluridine
Capecitabine EP Impurity B
CAPTOPRIL DISULFIDE
Canagliflozin Dimer
alpha-Capecitabine
5'-Deoxy-5-fluoro-N-[(2-methylbutoxy)carbonyl]cytidine
(2S)-1-[(2S)-2-Methyl-3-Methylsulfinylpropanoyl]pyrrolidine-2-carboxylic acid
5'-deoxy-5-fluore-N-[(pentoyloxy)carbonyl]cytidine 2',3'-diacetate
pentyl(1-((2R,3R,4R,5R)-3,4-bis(((2S,3R,4S,5R)-3,4-dihydroxy-5-methyltetrahydrofuran-2-yl)oxy)-5-methyltetrahydrofuran-2-yl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate
5'-Deoxy-5-fluorocytidine
3'-O-(5'-Deoxy-α-D-ribofuranosyl) Capecitabine
Capecitabine-2',3'-cyclic Carbonate
5'-Deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine
CAPECITABINE related substance USP
2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine