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GRA Ex-25

GRA Ex-25 ??? ???
?? ??:
307983-31-9
???:
GRA Ex-25
???(??):
GRA Ex-25;GRA Ex-25[GRA-Ex-25;GRA Ex-25 USP/EP/BP;GCGR,inhibit,GRA Ex 25,Inhibitor,GRA Ex-25,Glucagon Receptor,GRA Ex25;3-(4-((1-(trans-4-(tert-Butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid;β-Alanine, N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-;3-{[4-({1-[(1r,4r)-4-tert-butylcyclohexyl]{[4-(trifluoromethoxy)phenyl]carbamoyl}amino}methyl)phenyl]formamido}propanoic acid;B-Alanine, N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-
CBNumber:
CB11872296
???:
C29H36F3N3O5
??? ??:
563.61
MOL ??:
307983-31-9.mol

GRA Ex-25 ??

???
152-154 °C
?? ?
726.3±60.0 °C(Predicted)
??
1.28±0.1 g/cm3(Predicted)
?? ??
Sealed in dry,Store in freezer, under -20°C
???
DMF:25.0(Max Conc. mg/mL);44.36(Max Conc. mM)
DMSO:28.5(Max Conc. mg/mL);50.57(Max Conc. mM)
DMF:PBS (pH 7.2) (1:8):0.1(Max Conc. mg/mL);0.18(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);17.74(Max Conc. mM)
??? ??
??? ??
?? ?? (pKa)
4.29±0.10(Predicted)
??
White to off-white

??

GRA Ex-25 C??? ??, ??, ??

GRA Ex-25 ?? ?? ? ???

???

?? ??


GRA Ex-25 ?? ??

???( 60)?? ??
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