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TYRPHOSTIN A25

TYRPHOSTIN A25 ??? ???
?? ??:
118409-58-8
???:
TYRPHOSTIN A25
???(??):
AG 82;RG-50875;TYRPHOSTIN 25;TYRPHOSTIN A25;TYROPHOSTIN A25;TYRPHOSTIN AG 82;TYRPHOSTIN RG 50875;RARECHEM AL BX 0070;TYRPHOSTIN A25 99+%;TYRPHOSTIN A25 USP/EP/BP
CBNumber:
CB1178038
???:
C10H6N2O3
??? ??:
202.17
MOL ??:
118409-58-8.mol

TYRPHOSTIN A25 ??

???
~220°C dec.
?? ?
500.8±50.0 °C(Predicted)
??
1.569±0.06 g/cm3(Predicted)
?? ??
2-8°C
???
DMSO: >50mg/mL, ??, ???~???
??? ??
?? ??? ??
?? ?? (pKa)
7.10±0.23(Predicted)
??
???
???
???
CAS ??????
118409-58-8

??

WGK ?? 3

TYRPHOSTIN A25 C??? ??, ??, ??

??? ??

Yellow Green Powder

?? ??

A cell-permeable, reversible, and competitive inhibitor of substrate binding on protein tyrosine kinases. Inhibits epidermal growth factor receptor tyrosine kinase (IC50 = 3 μM) and the GTPase activity of transducin (IC50 = 7 μM). Blocks the induction of inducible nitric oxide synthase in glial cells. Induces apoptosis in human leukemic cell lines. Also reported to inhibit guanylyl cyclase.

TYRPHOSTIN A25 ?? ?? ? ???

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TYRPHOSTIN A25 ?? ??

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