?? ???
|
|
?? ??? ??
- ???
- -66°C
- ??
- [α]D20+1.410～+1.418
- ?? ?
- 35 °C (6 mmHg)
- ??
- 1.093 g/mL at 20 °C(lit.)
- ???
- n
20/D 1.413
- ???
- 49 °C
- ?? ??
- Flammables area
- ??? ??
- ??
- ?? ?? (pKa)
- 13.07±0.20(Predicted)
- ??
- ??~??? ??
- Specific Gravity
- 1.09
- ???
- ???, ????
- ??
- Moisture Sensitive
- Merck
- 14,6094
- BRN
- 1720586
- InChIKey
- LPEKGGXMPWTOCB-UHFFFAOYSA-N
- LogP
- -0.670 (est)
- CAS ??????
- 547-64-8(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 10-36/37 | ||
| ????? | 24-24/25 | ||
| ????(UN No.) | UN 3272 3/PG 3 | ||
| WGK ?? | 1 | ||
| RTECS ?? | OD5670000 | ||
| F ?????? | 21 | ||
| TSCA | Yes | ||
| ?? ?? | 3.2 | ||
| ???? | III | ||
| HS ?? | 29181100 | ||
| ?? ?? ??? | 547-64-8(Hazardous Substances Data) | ||
| ???? ?? | KE-24319 |
?? ??? C??? ??, ??, ??
??
Methyl lactate is a compound with many uses. It can be used as a solvent, as a starting material for the manufacture of polyiactic acid, or as a starting material for numerous other reactions. For example, it can be used as intermediate in lactic acid purification, and as building block in the synthesis of chiral components, e.g., pesticides, and as a starting material for lactide manufacture.??? ??
Methyl lactate is a colorless transparent liquid. It is soluble/miscible in water, acetone, ethyl alcohol, and other organic solvents. It is used as a cellulose acetate solvent.??
Methyl lactate is used as a solvent for nitrocellulose, cellulase acetate, cellulase acetobutyrote and cellulase acetaprapionate. It is used in the manufacture of lacquers and dopes where it contributes high tolerance for diluents, good flaw and blush resistance.??
ChEBI: Methyl lactate is a lactate ester resulting from the formal condensation of the carboxy group of 2-hydroxypropanoic acid with methanol. It has a role as a metabolite. It is a lactate ester and a methyl ester.???
Moderate fire risk.Safety Profile
Methyl lactate has been classed as non-irritant to the eyes of guinea pigs.The estimated average lethal dose for the female rat following i.p. injection of methyl lactate was >2000 mg/kg body weight. Observations included narcosis, respiratory distress and peritoneal adhesions. The estimated non toxic dose and estimated maximum dose without gross lesions at necropsy was 500 mg/kg body weight.
Synthesis
Methyl lactate is prepared by the esterification of methyl alcohol with lactic acid.Purification Methods
Methyl lactate is easily hydrolyzed and often contains impurities such as free lactic acid, methanol and water. Free acid can be removed by washing after neutralization with alkali. Moisture can be removed by azeotropic distillation of an azeotropic mixture with benzene. Then, it was purified by distillation under reduced pressure. Since calcium chloride and the like form molecular compounds with methyl lactate, they cannot be used as desiccants. When the methyl lactate is mixed with water, it can be extracted and recovered with benzene, ether, etc.?? ??? ?? ?? ? ???
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???( 219)?? ??
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