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VRT752271

VRT752271 ??? ???
?? ??:
869886-67-9
???:
VRT752271
???(??):
CS-725;VRT752271;Padsevonil;Ulixertinib;VRT752271 HCl;BVD-523 ( VRT752271);Ulixertinib (BVD-523);Ulixertinib, VRT752271;VRT-752271(Ulixertinib);Ulixertinib 869886-67-9
CBNumber:
CB02630104
???:
C21H22Cl2N4O2
??? ??:
433.33
MOL ??:
869886-67-9.mol

VRT752271 ??

?? ?
682.8±55.0 °C(Predicted)
??
1.359
?? ??
Store at -20°C
???
DMSO:93.0(Max Conc. mg/mL);214.62(Max Conc. mM)
Ethanol:43.0(Max Conc. mg/mL);99.23(Max Conc. mM)
?? ?? (pKa)
13.34±0.50(Predicted)
??? ??
??
??
White to off-white
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
HS ?? 2933998090
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

VRT752271 C??? ??, ??, ??

??

Ulixertinib is a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Inhibits cell proliferation. Anti-cancer.

VRT752271 ?? ?? ? ???

???

?? ??


VRT752271 ?? ??

???( 147)?? ??
??? ?? ??? ?? ?? ? ??
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VRT752271 ?? ??:

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