3-[3-(4'-ブロモ-1,1'-ビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシクマリン MSDS

Brodifacoum

3-[3-(4'-ブロモ-1,1'-ビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシクマリン 化學(xué)特性,用途語(yǔ),生産方法

説明

Brodifacoum is a 4-hydroxycoumarin anticoagulant that acts as a vitamin K antagonist. It was registered as a pesticide in 1979 in the United States although in 2008 it was made a restricted use pesticide by the Environmental Protection Agency. This means it can only be used by certified pesticide applicators; however, the makers of D-Con which contains 0.005% brodifacoum by weight have challenged this and brodifacoum is currently available in D-Con and in various other pesticide products for the eradication of mice and rats although it is also used on larger mammals such as possums. Brodifacoum currently remains available to the general public.

化學(xué)的特性

White Solid

使用

Brodifacoum is a highly lethal vitamin K antagonist anticoagulant poison. In recent years, Broadifacoum, has become one of the world's most widely used pesticides.

危険性

Poison, anticoagulant.

環(huán)境運(yùn)命予測(cè)

Brodifacoum, like other hydroxycoumarins, interferes with the production of vitamin K–dependent coagulation factors. Vitamin K is a cofactor for the carboxylation of specific glutamic acid groups in coagulation factors II (prothrombin), VII, IX, and X. During this step, vitamin K is oxidized to vitamin K 2,3-epoxide. The regeneration of vitamin K by vitamin K 2,3-epoxide reductase is prevented by brodifacoum. As a result, dysfunctional decarboxy-coagulation factors are produced and coagulation is impaired. Brodifacoum is over 100 times more potent than warfarin on a molar basis in rats.

代謝経路

The fate of brodifacoum in soils and plants has not been studied in detail because the compound is usually applied as a pelleted bait or in a wax block. This limits its dissipation in the environment. Studies in animals have been conducted as part of the assessment of safety and to investigate mode of action.

3-[3-(4'-ブロモ-1,1'-ビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシクマリン 上流と下流の製品情報(bào)

原材料

準(zhǔn)備製品

56073-10-0(3-[3-(4'-ブロモ-1,1'-ビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシクマリン)キーワード:

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• 56073-10-0
• KLERAT
• KLERAT(R)
• FORWARAT
• HAVOC
• BROBAIT
• BRODIFACOUM
• 3-(3-(4'-bromo-(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxy-2h-1-benzopyran-2-one
• 3-(3-(4'-Bromo-(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-napthalenyl)-4-hydroxycoumarin
• SOREX BRODIFACOUM RAT
• TALON(R)
• NOFAR(R)
• MOUSE BAIT
• WEATHERBLOK(R)
• 2h-1-benzopyran-2-one,3-(3-(4’-bromo(1,1’-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1
• 3-(3-(4’-bromo-1,1’-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-hydroxyc
• 3-(3-(4’-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphth-1-yl)-4-hydroxycoumari
• 3-[3-(4’-bromo[1,1’-biphenyl]4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydrox
• 3-[3-[4’-Bromo[1,1’-biphenyl]-4-yl]-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-benzopyran-2-one
• 4-hydroxy-3-(3-(4’-bromo-4-biphenylyl)-1,2,3,4-tetrahydro-1-naphthyl)coumarin
• brodifakum
• bromfenacoum
• coumarin,3-(3-(4’-bromo-1,1’-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthyl)-4-h
• -naphthalenyl)-4-hydroxy-
• pp581
• BRODIFACOUM, 50MG, NEAT
• BRODIFACOUM PESTANAL 100 MG
• 3-[3-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl]-4-hydroxy-2H-1-benzopyran-2-one
• Brodifacoun
• 2H-1-Benzopyran-2-one, 3-3-(4-bromo1,1-biphenyl-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl-4-hydroxy-
• brodifacoum (bsi,iso)
• ブロフェナコウム
• ブロジファクム
• ボリッド
• クレラット
• ラタックプラス
• ラタク+
• タロン
• 3-[3-(4'-ブロモビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシ-2H-1-ベンゾピラン-2-オン
• ケレラット
• ブロジファコウム
• 3-[3-(4'-ブロモ-1,1'-ビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシクマリン
• タロンロデンチシド
• ブロジファコム標(biāo)準(zhǔn)品
• ブロディファコウム標(biāo)準(zhǔn)品
• CS_N-11329-50MG_ブロジファクム
• ブロジファクム STANDARD
• ブロディファコウム
• ブロジファクム Standard, 100 μg/mL in Methanol
• 3-(3-{4'-ブロモ-[1,1'-ビフェニル]-4-イル}-1,2,3,4-テトラヒドロナフタレン-1-イル)-4-ヒドロキシ-2H-クロメン-2-オン
• 3-[3-(4′-ブロモビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシ-2H-1-ベンゾピラン-2-オン
• 3-[3-(4′-ブロモ-1,1′-ビフェニル-4-イル)-1,2,3,4-テトラヒドロナフタレン-1-イル]-4-ヒドロキシクマリン
• スーパーワルファリン
• 抗凝固薬
• 殺鼠剤
• 生活関係標(biāo)準(zhǔn)物質(zhì)
• 食料品