tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate
- CAS No.
- 107017-73-2
- Chemical Name:
- tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate
- Synonyms
- tert-Butyl [1-(Hydroxymethyl)cyclopropyl]carbamate;tert-butyl N-[1-(hydroxymethyl)cyclopropyl]carbamate;SKL325;Boc-ACPC-ol;Boc-1-Aminocyclopropylmethanol;N-Boc-1-AMinocyclopropylMethanol;1-(Boc-amino)cyclopropylmethanol;Boc-1-aminocyclopropane methanol;1-Boc-Amino-cyclopropanemethanol;N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
- CBNumber:
- CB91508201
- Molecular Formula:
- C9H17NO3
- Molecular Weight:
- 187.24
- MDL Number:
- MFCD09749954
- MOL File:
- 107017-73-2.mol
- MSDS File:
- SDS
| Melting point | 81.0 to 85.0 °C |
|---|---|
| Boiling point | 294.5±9.0 °C(Predicted) |
| Density | 1.11±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 12.24±0.20(Predicted) |
| color | White to Orange to Green |
| InChI | InChI=1S/C9H17NO3/c1-8(2,3)13-7(12)10-9(6-11)4-5-9/h11H,4-6H2,1-3H3,(H,10,12) |
| InChIKey | HFMAZNJKNNRONT-UHFFFAOYSA-N |
| SMILES | C(OC(C)(C)C)(=O)NC1(CO)CC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P280-P305+P351+P338-P310 |
| HS Code | 2924297099 |
tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B4251 | [1-(tert-Butoxycarbonylamino)cyclopropyl]methanol >97.0%(GC) | 107017-73-2 | 200mg | $41 | 2024-03-01 | Buy |
| TCI Chemical | B4251 | [1-(tert-Butoxycarbonylamino)cyclopropyl]methanol >97.0%(GC) | 107017-73-2 | 1g | $132 | 2024-03-01 | Buy |
| TRC | B809783 | tert-ButylN-[1-(Hydroxymethyl)cyclopropyl]carbamate | 107017-73-2 | 250mg | $90 | 2021-12-16 | Buy |
| Apolloscientific | OR350017 | Boc-1-Aminocyclopropylmethanol 98% | 107017-73-2 | 1g | $37 | 2021-12-16 | Buy |
| ChemScene | CS-D0180 | tert-butyl(1-(hydroxymethyl)cyclopropyl)carbamate >98.0% | 107017-73-2 | 5g | $78 | 2021-12-16 | Buy |
tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Chemical Properties,Uses,Production
Physical Form
Solid
Uses
Tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate could be converted into spirocyclopropanated analogues 14-CP and 14-CT of the insecticide Thiacloprid [1]. It can also be transformed into spirocyclopropanated analogs of Imidacloprid. This compound could be used to synthesize spirocyclopropanated five-membered ring analog 4-(3,5-Dichlorophenyl)-N-isopropyl-5-oxo-4,6-diazaspiro- [2.4]heptane-6-carboxamide[2].
Preparation
Tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate can be synthesized in three steps (40 % overall yield) from N, Ndibenzyl-2-benzyloxyacetamide starting with its reductive cyclopropanation (the de Meijere variant of the so-called Kulinkovich reaction). It can also be prepared in 56 % overall yield by monohydrolysis of commercially available diethyl cyclopropane-1,1-dicarboxylate followed by Curtius degradation of the carboxylic acid residue and subsequent reduction of the ester moiety[1].
References
[1] Brackmann F, et al. Synthesis of Spirocyclopropanated Analogues of Imidacloprid and Thiacloprid. European Journal of Organic Chemistry, 2005; 2005: 600-609.
[2] Brackmann F, et al. Synthesis of Spirocyclopropanated Analogues of Iprodione. European Journal of Organic Chemistry, 2005; 2005: 2250-2258.
tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29863 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19230 | 58 |
| Chengdu Feibo Pharm Technology Co., Ltd | +86 028-84641798 15982321820 | abby@arkpharm.com | China | 10922 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49732 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
View Lastest Price from tert-Butyl (1-(hydroxymethyl)cyclopropyl)carbamate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-10-01 | Boc-1-Aminocyclopropylmethanol
107017-73-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2022-05-25 | N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
107017-73-2
|
US $1.10 / g | 1g | 99.0% Min | 100 Tons | Dideu Industries Group Limited | |
 |
2019-09-05 | N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
107017-73-2
|
US $5.50 / KG | 2KG | 96%-99% | 100kg | Career Henan Chemical Co |
-
- Boc-1-Aminocyclopropylmethanol
107017-73-2
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
107017-73-2
- US $1.10 / g
- 99.0% Min
- Dideu Industries Group Limited
-
- N-BOC-1-AMINO-CYCLOPROPANEMETHANOL
107017-73-2
- US $5.50 / KG
- 96%-99%
- Career Henan Chemical Co
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