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ChemicalBook >> CAS DataBase List >>1-O-Hexyl-2,3,5-trimethylhydroquinone

1-O-Hexyl-2,3,5-trimethylhydroquinone

CAS No.
148081-72-5
Chemical Name:
1-O-Hexyl-2,3,5-trimethylhydroquinone
Synonyms
CS-2408;HX-1171;4-hexoxy-2;1-O-Hexyl-2;HX-1171(HTHQ);HTHQ(HX-1171);6-trimethylphenol;HTHQ, 10 mM in DMSO;5-trimethylhydroquinone;HEXYLOXY TRIMETHYLPHENOL
CBNumber:
CB61175507
Molecular Formula:
C15H24O2
Molecular Weight:
236.35
MDL Number:
MFCD00927896
MOL File:
148081-72-5.mol
MSDS File:
SDS
Last updated:2025-06-12 13:02:17

1-O-Hexyl-2,3,5-trimethylhydroquinone Properties

Melting point 72.5-73°C
Boiling point 357.8±37.0 °C(Predicted)
Density 0.971±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,2-8°C
solubility Chloroform:soluble
form powder to crystal
pka 11.22±0.30(Predicted)
color White to Light yellow to Dark green
LogP 5.255 (est)
FDA UNII 70BK60I8RP

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2909.50.5000
NFPA 704
0
2 0

1-O-Hexyl-2,3,5-trimethylhydroquinone price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical H1741 4-(Hexyloxy)-2,3,6-trimethylphenol 148081-72-5 50MG $43 2024-03-01 Buy
TCI Chemical H1741 4-(Hexyloxy)-2,3,6-trimethylphenol 148081-72-5 250MG $129 2024-03-01 Buy
Cayman Chemical 22652 HX 1171 ≥98% 148081-72-5 50mg $86 2024-03-01 Buy
Cayman Chemical 22652 HX 1171 ≥98% 148081-72-5 100mg $135 2024-03-01 Buy
TRC H325000 1-O-Hexyl-2,3,5-trimethylhydroquinone 148081-72-5 500mg $480 2021-12-16 Buy
Product number Packaging Price Buy
H1741 50MG $43 Buy
H1741 250MG $129 Buy
22652 50mg $86 Buy
22652 100mg $135 Buy
H325000 500mg $480 Buy

1-O-Hexyl-2,3,5-trimethylhydroquinone Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Low Melting Solid

Uses

HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals[1][2].

in vivo

HTHQ (50-200 mg/kg; oral administration; for 4 weeks; specific pathogen-free male Sprague Dawley rats) treatment significantly improves liver weight and serum chemistry level. HTHQ reduces hydroxyproline and malondialdehyde level in the liver. HTHQ treatment also reduces fibrotic septa. HTHQ administration shows reduced mRNA level of PDGF (Plateletderived growth factor) , α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β) than DMN-induced hepetic fibrosis animals in the liver tissue[2].

Animal Model:48 specific pathogen-free male Sprague Dawley (SD) rats (6-week-old ) with dimethylnitrosamine (DMN) [2]
Dosage:50 mg/kg, 100 mg/kg, 200 mg/kg
Administration:Oral administration; for 4 weeks
Result:Improved against DMN-induced liver fibrosis in male SD rats.

References

[1] Park HJ, et al. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells. Molecules. 2019 Mar 1;24(5). pii: E867. DOI:10.3390/molecules24050867
[2] Jung YR et al. Inhibitory Effect of 1-O-Hexyl-2,3,5-Trimethylhydroquinone on Dimethylnitrosamine-induced Liver Fibrosis in Male SD Rats. Toxicol Res. 2010 Sep;26(3):193-201. DOI:10.5487/TR.2010.26.3.193

700-13-0
111-27-3
148081-72-5
Synthesis of 1-O-Hexyl-2,3,5-trimethylhydroquinone from Trimethylhydroquinone and 1-Hexanol

1-O-Hexyl-2,3,5-trimethylhydroquinone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 72)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28172 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29808 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5745 58
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
+86-86-22-87899925 +86-8618522618860 18522618860@163.com China 694 58
TargetMol Chemicals Inc.
+17819995354 marketing@targetmol.com United States 32295 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6391 58
LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24727 58

View Lastest Price from 1-O-Hexyl-2,3,5-trimethylhydroquinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
HTHQ pictures 2025-06-12 HTHQ
148081-72-5
US $37.00-77.00 / mg 98.78% 10g TargetMol Chemicals Inc.
1-O-Hexyl-2,3,5-trimethylhydroquinone pictures 2019-12-24 1-O-Hexyl-2,3,5-trimethylhydroquinone
148081-72-5
US $1.00 / g 1g 99% 20kg Career Henan Chemical Co
  • HTHQ pictures
  • HTHQ
    148081-72-5
  • US $37.00-77.00 / mg
  • 98.78%
  • TargetMol Chemicals Inc.

148081-72-5(1-O-Hexyl-2,3,5-trimethylhydroquinone)Related Search:

4-(Hexyloxy)-2,3,6-triMethyl-phenol 4-Hexyloxy-2,3,6-triMethylphenol HX-1171 1-O-Hexyl-2 4-hexoxy-2 4-HEXOXY-2;3;6-TRIMETHYLPHENOL;1-O-HEXYL-2;3;5-TRIMETHYLHYDROQUINONE 5-trimethylhydroquinone 6-trimethylphenol 4-hexoxy-2,3,6-trimethylphenol CS-2408 HTHQ(1-O-Hexyl-2,3,5-trimethylhydroquinone) Phenol, 4-(hexyloxy)-2,3,6-trimethyl- HEXYLOXY TRIMETHYLPHENOL HX-1171(HTHQ) HTHQ(HX-1171) BTT 105,BTT105,inhibit,BTT-105,HTHQ,HX1171,Reactive Oxygen Species,Inhibitor,HX-1171 HTHQ, 10 mM in DMSO 148081-72-5 Detergents Mutagenesis Research Chemicals