1-O-Hexyl-2,3,5-trimethylhydroquinone
- CAS No.
- 148081-72-5
- Chemical Name:
- 1-O-Hexyl-2,3,5-trimethylhydroquinone
- Synonyms
- CS-2408;HX-1171;4-hexoxy-2;1-O-Hexyl-2;HX-1171(HTHQ);HTHQ(HX-1171);6-trimethylphenol;HTHQ, 10 mM in DMSO;5-trimethylhydroquinone;HEXYLOXY TRIMETHYLPHENOL
- CBNumber:
- CB61175507
- Molecular Formula:
- C15H24O2
- Molecular Weight:
- 236.35
- MDL Number:
- MFCD00927896
- MOL File:
- 148081-72-5.mol
- MSDS File:
- SDS
Melting point | 72.5-73°C |
---|---|
Boiling point | 357.8±37.0 °C(Predicted) |
Density | 0.971±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform:soluble |
form | powder to crystal |
pka | 11.22±0.30(Predicted) |
color | White to Light yellow to Dark green |
LogP | 5.255 (est) |
FDA UNII | 70BK60I8RP |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P305+P351+P338 | |||||||||
HS Code | 2909.50.5000 | |||||||||
NFPA 704 |
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1-O-Hexyl-2,3,5-trimethylhydroquinone price More Price(23)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | H1741 | 4-(Hexyloxy)-2,3,6-trimethylphenol | 148081-72-5 | 50MG | $43 | 2024-03-01 | Buy |
TCI Chemical | H1741 | 4-(Hexyloxy)-2,3,6-trimethylphenol | 148081-72-5 | 250MG | $129 | 2024-03-01 | Buy |
Cayman Chemical | 22652 | HX 1171 ≥98% | 148081-72-5 | 50mg | $86 | 2024-03-01 | Buy |
Cayman Chemical | 22652 | HX 1171 ≥98% | 148081-72-5 | 100mg | $135 | 2024-03-01 | Buy |
TRC | H325000 | 1-O-Hexyl-2,3,5-trimethylhydroquinone | 148081-72-5 | 500mg | $480 | 2021-12-16 | Buy |
1-O-Hexyl-2,3,5-trimethylhydroquinone Chemical Properties,Uses,Production
Chemical Properties
Pale Yellow Low Melting Solid
Uses
HTHQ (1-O-hexyl-2,3,5-trimethylhydroquinone) is a potent lipophilic phenolic antioxidant. HTHQ has considerable anti-oxidative activity by directly reacting with reactive oxygen species (ROS) and scavenging ROS to form more stable free radicals[1][2].
in vivo
HTHQ (50-200 mg/kg; oral administration; for 4 weeks; specific pathogen-free male Sprague Dawley rats) treatment significantly improves liver weight and serum chemistry level. HTHQ reduces hydroxyproline and malondialdehyde level in the liver. HTHQ treatment also reduces fibrotic septa. HTHQ administration shows reduced mRNA level of PDGF (Plateletderived growth factor) , α-SMA (α-smooth muscle actin) and TGF-β (transforming growth factor-β) than DMN-induced hepetic fibrosis animals in the liver tissue[2].
Animal Model: | 48 specific pathogen-free male Sprague Dawley (SD) rats (6-week-old ) with dimethylnitrosamine (DMN) [2] |
Dosage: | 50 mg/kg, 100 mg/kg, 200 mg/kg |
Administration: | Oral administration; for 4 weeks |
Result: | Improved against DMN-induced liver fibrosis in male SD rats. |
References
[1] Park HJ, et al. 1-O-Hexyl-2,3,5-Trimethylhydroquinone Ameliorates l-DOPA-Induced Cytotoxicity in PC12 Cells. Molecules. 2019 Mar 1;24(5). pii: E867. DOI:10.3390/molecules24050867
[2] Jung YR et al. Inhibitory Effect of 1-O-Hexyl-2,3,5-Trimethylhydroquinone on Dimethylnitrosamine-induced Liver Fibrosis in Male SD Rats. Toxicol Res. 2010 Sep;26(3):193-201. DOI:10.5487/TR.2010.26.3.193
1-O-Hexyl-2,3,5-trimethylhydroquinone Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29808 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5745 | 58 |
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32295 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24727 | 58 |
View Lastest Price from 1-O-Hexyl-2,3,5-trimethylhydroquinone manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2025-06-12 | HTHQ
148081-72-5
|
US $37.00-77.00 / mg | 98.78% | 10g | TargetMol Chemicals Inc. | ||
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2019-12-24 | 1-O-Hexyl-2,3,5-trimethylhydroquinone
148081-72-5
|
US $1.00 / g | 1g | 99% | 20kg | Career Henan Chemical Co |
-
- HTHQ
148081-72-5
- US $37.00-77.00 / mg
- 98.78%
- TargetMol Chemicals Inc.
-
- 1-O-Hexyl-2,3,5-trimethylhydroquinone
148081-72-5
- US $1.00 / g
- 99%
- Career Henan Chemical Co