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ChemicalBook >> CAS DataBase List >>1,4,8,11-TETRAAZACYCLOTETRADECANE

1,4,8,11-TETRAAZACYCLOTETRADECANE

CAS No.
295-37-4
Chemical Name:
1,4,8,11-TETRAAZACYCLOTETRADECANE
Synonyms
CYCLAM;jm1498;Cyclam, 98+%;otetradecane;Compound PDK0168;Valine Impurity 134;1,4,8,11-TetraazacycL;Plerixafor Impurity 67;cyclaM, Methanol adduct;Plerixafor intermediate
CBNumber:
CB3136889
Molecular Formula:
C10H24N4
Molecular Weight:
200.32
MDL Number:
MFCD00005105
MOL File:
295-37-4.mol
MSDS File:
SDS
Last updated:2025-01-27 09:38:02

1,4,8,11-TETRAAZACYCLOTETRADECANE Properties

Melting point 184-186 °C (lit.)
Boiling point 328.07°C (rough estimate)
Density 1.0203 (rough estimate)
refractive index 1.5200 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility Dichloromethane, Methanol
form Fluffy Needle-Like Crystalline Powder
pka 10.90±0.20(Predicted)
color White
Water Solubility Soluble in water.
Sensitive Air Sensitive
BRN 111811
InChIKey MDAXKAUIABOHTD-UHFFFAOYSA-N
CAS DataBase Reference 295-37-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII EP5AZ544VP
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  XA5254800
F  3-9-34
HS Code  29339900
Toxicity LD50 intraperitoneal in mouse: 371mg/kg
NFPA 704
0
2 0

1,4,8,11-TETRAAZACYCLOTETRADECANE price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 259160 1,4,8,11-Tetraazacyclotetradecane 98% (GC) 295-37-4 1g $79.8 2024-03-01 Buy
Sigma-Aldrich 259160 1,4,8,11-Tetraazacyclotetradecane 98% (GC) 295-37-4 5g $194 2024-03-01 Buy
TCI Chemical T1597 1,4,8,11-Tetraazacyclotetradecane >98.0%(T) 295-37-4 1g $91 2024-03-01 Buy
TCI Chemical T1597 1,4,8,11-Tetraazacyclotetradecane >98.0%(T) 295-37-4 5g $302 2024-03-01 Buy
Alfa Aesar A11516 1,4,8,11-Tetraazacyclotetradecane, 98+% 295-37-4 1g $65.65 2024-03-01 Buy
Product number Packaging Price Buy
259160 1g $79.8 Buy
259160 5g $194 Buy
T1597 1g $91 Buy
T1597 5g $302 Buy
A11516 1g $65.65 Buy

1,4,8,11-TETRAAZACYCLOTETRADECANE Chemical Properties,Uses,Production

Chemical Properties

white fluffy needle-like crystalline powder

Uses

Reagent used in the preparation of Plerixafor derivatives.

Uses

1,4,8,11-Tetraazacyclotetradecane is used in the synthesis of molecules with electroactive cavities. It acts as a nitrogen crown ether analogue and as an antioxidant in rubber. It is also used in the preparation of plerixafor derivatives.

Uses

1,4,8,11-Tetraazacyclotetradecane is macrocyclic ligand that is used as an antioxidant in rubber and has been shown to suppress oxidation catalyzed by some metal ions.

Definition

ChEBI: 1,4,8,11-tetraazacyclotetradecane is a saturated organic heteromonocyclic parent, a crown amine and an azacycloalkane. It derives from a hydride of a cyclotetradecane.

General Description

1,4,8,11-Tetraazacyclotetradecane is an azamacrocycle that forms more stable metal complexes as compared to open chain ligands.

Purification Methods

Purify cyclam by recrystallisation from dioxane (white needles), and it sublimes above 120o. It has been distilled, b 132-140o/4-8mm. It forms complexes with metals and gives a sparingly soluble nitrate salt, m 205o(dec), which crystallises from H2O and is dried at 150o. [UV: Bosnich et al. Inorg Chem 4 1102 1963, van Alphen Recl Trav Chim Pays-Bas 56 343 1937, Beilstein 26 III/IV 1647.]

4741-99-5
295-37-4
Synthesis of 1,4,8,11-TETRAAZACYCLOTETRADECANE from N,N'-Bis(2-aminoethyl)-1,3-propanediamine
Global( 327)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 19837 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21622 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29856 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com China 2930 58
Changzhou Ansciep Chemical Co., Ltd. 		+86 519 86305871 sales@ansciepchem.com CHINA 4241 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29807 58
Univar Solutions(China) Co., Ltd. 		+8615902132654 ivy.zhuang@univarsolutions.com China 654 58
Shandong Hengshannuode Pharmaceutical Technology Co., Ltd. 		+8615065888978 admin@hsnordpharma.com China 92 58

View Lastest Price from 1,4,8,11-TETRAAZACYCLOTETRADECANE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,4,8,11-TETRAAZACYCLOTETRADECANE pictures 2025-05-16 1,4,8,11-TETRAAZACYCLOTETRADECANE
295-37-4
 US $100.00 / kg 1kg 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
1,4,8,11-Tetraazacyclotetradecane pictures 2023-11-13 1,4,8,11-Tetraazacyclotetradecane
295-37-4
 US $3840.00 / Kg/Bag 1Kg/Bag 99% 5 tons Wuhan Boye Science And Technology Development Co., Ltd.
1,4,8,11-Tetraazacyclotetradecane 98% (GC) pictures 2021-07-02 1,4,8,11-Tetraazacyclotetradecane 98% (GC)
295-37-4
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
1,4,8-Tris(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane 1,4,8-Tris(trifluoroacetyl)cyclaM cyclaM, Methanol adduct 1,4,8,11-Tetraazacyclotetradecane 98% (GC) jm1498 CYCLAM Cyclam, 98+% 1,4,8,11-TETRAAZACYCLOTETRADECANE Cyclam=1,4,8,11-Tetraazacyclotetradecane 1,4,8,11-Tetraazacyclotetradecane, 99+% 1,4,8,11-Tetraazacyclotetradecane,min.98%CYCLAM 1,4,8,11-TETRAAZACYCLOTETRADECANE(CYCLAM) 1,4,8,11-Tetraazacyclotetradecane 98% 1,4,8,11-TETRAAZACYCLOTETRADECANE, 98+% (1α,4β,8β,11α)-1,4,8,11-Tetraazacyclotetradecane 1,4,8,11-tetraazacyclotetradecane Hexa(trifluoroacetate) 1,1',1''-(1,4,8,11-Tetraazacyclotetradecane-1,4,8-triyl)tris[2,2,2-trifluoro-ethanone 1,4,8,11-Tetraazacyclotetradecane, 99+% 1GR Tetraazacyclotetradecane 1,4,8,11-TetraazacycL otetradecane 1,4,8,11-tetrazacyclotetradecane Plerixafor 1,4,8,11-Tetraazacyclotetradecane Plerixafor intermediate Plerixafor 1,4,8,11-Tetraazacyclotetradecane/ 1,4,8,11-Tetraazacyclotetradecane 1,4,8,11-TETRAAZACYCLOTETRADECANE 295-37-4 1,4,8,11-Tetraazacyclotetradecane (6CI, 7CI, 8CI, 9CI, ACI) Compound PDK0168 Plerixafor Impurity 67 Valine Impurity 134 295-37-4 C10H20N4 C10H24N4 C16H21F9N4O3 Synthetic Reagents Macrocycles for Host-Guest Chemistry Azacrown Ethers Crown Ethers Chelation/Complexation Compounds Ring Systems organic amine Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Azacrown Ethers Crown Ethers Functional Materials Macrocycles for Host-Guest Chemistry Achiral Nitrogen Cy-N