6-Aminonicotinamid
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6-Aminonicotinamid Eigenschaften
- Schmelzpunkt:
- 245-248 °C (lit.)
- Siedepunkt:
- 251.97°C (rough estimate)
- Dichte
- 1.2620 (rough estimate)
- Brechungsindex
- 1.6910 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- insoluble in H2O; insoluble in EtOH; ≥13.7 mg/mL in DMSO
- Aggregatzustand
- powder to crystal
- pka
- 15.66±0.50(Predicted)
- Farbe
- White to Light yellow
- Wasserl?slichkeit
- Soluble in Dimethyl sulfoxide (DMSO). Insoluble in water.
- BRN
- 116042
- CAS Datenbank
- 329-89-5(CAS DataBase Reference)
- NIST chemische Informationen
- Nicotinamide, 6-amino-(329-89-5)
- EPA chemische Informationen
- 6-Aminonicotinamide (329-89-5)
Sicherheit
Kennzeichnung gef?hrlicher | T | ||
---|---|---|---|
R-S?tze: | 61 | ||
S-S?tze: | 53-45 | ||
RIDADR | 1655 | ||
WGK Germany | 3 | ||
RTECS-Nr. | US4550000 | ||
Hazard Note | Toxic | ||
HazardClass | 6.1 | ||
PackingGroup | II | ||
HS Code | 29333990 |
6-Aminonicotinamid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R61:Kann das Kind im Mutterleib sch?digen.S-S?tze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn m?glich, dieses Etikett vorzeigen).
Verwenden
antineoplastic, apoptosis inducerDefinition
ChEBI: A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 6-aminonicotinic acid with ammonia. An inhibitor of the NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase, it interferes with glycolysis resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, such as cisplatin, in killing cancer cells.Allgemeine Beschreibung
White crystalline solid.Air & Water Reaktionen
Insoluble in water.Reaktivit?t anzeigen
An amine and amide. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition 6-Aminopyridine-3-carboxamide emits toxic fumes of NOx.Brandgefahr
Flash point data for 6-Aminopyridine-3-carboxamide are not available; however, 6-Aminopyridine-3-carboxamide is probably combustible.6-Aminonicotinamid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-Aminonicotinamid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 181)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5906 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29810 | 58 |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 |
sale04@alfachem.cn | China | 11836 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32161 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23541 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9911 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
329-89-5(6-Aminonicotinamid)Verwandte Suche:
N,N-Dimethylpyridin-4-amin
Formamid
2-Pyridylamin
Nicotinamid
3-Pyridylamin
N,N-Dimethylformamid
Isonicotinamid
Pyridin-2-carboxamid
Paracetamol
5-Methyl-2-pyridylamin
6-Aminonicotinsaeure
CARBOXAMIDE
6-Aminonicotinamid
- 6-azanylpyridine-3-carboxamide
- Nicotinamide, 6-amino-
- Nicotinamide, 6-amino- (8CI)
- WLN: T6NJ BZ EVZ
- 6-Aminonikotinsaeureamid [German]
- 6-Aminonitoinamide
- 2-Amino-5-carbamoylpyridine
- 3-Pyridinecarboxamide, 6-amino-
- 6-amino-3-pyridinecarboxamid
- 6-amino-nicotinamid
- 6-Aminonicotinic acid amide
- 6-aminonicotinicacidamide
- 6-Amino-nicotinsaeureamid
- 6-Aminonikotinsaeureamid
- 6-AN
- 6-ANA
- Aminonicotinamide
- FDA 0121
- fda0121
- NSC 21206
- nsc21206
- U-8774
- 2-AMINOPYRIDINE-5-CARBOXAMIDE
- 6-AMINOPYRIDINE-3-CARBOXAMIDE
- 6-AMINONICOTINAMIDE
- 6-AMINO-3-PYRIDINECARBOXAMIDE
- 6-Aminoincotinamide
- 3-Pyridinecarboxamide,6-amino-(9CI)
- NSC-13128
- SR-4388
- 6-Aminonicotinamide >
- Antioxidant 40
- BRN 2034522
- 6-aminonicotinic amide
- 6-Aminonicotinamide 95+%
- Apremilast Impurity 126
- 329-89-5
- Heterocyclic Building Blocks
- Pyridines
- Building Blocks
- C6
- Heterocyclic Compounds
- Building Blocks
- C6
- Chemical Synthesis
- Heterocyclic Building Blocks
- AMIDE
- Pyridine series
- Amines
- Pyridines