MONOCLONAL ANTI-PLEKHA7 ANTIBODY PRODUCED IN MOUSE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Monoclonal Anti-PLEKHA7 antibody has been used in
- immunoblotting
- immunocytochemistry
- flow cytometry
Allgemeine Beschreibung
Monoclonal Anti-PLEKHA7 (mouse IgG2a isotype) is derived from the hybridoma PLK7 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic peptide corresponding to a sequence at the N-terminal region of human PLEKHA7, conjugated to KLH. PLEKHA7 contains WW (rsp5-domain), PH (pleckstrin homology), and CC (coiled-coil) domains.
Biochem/physiol Actions
PLEKHA7 (Pleckstrin homology domain containing, family A member 7) functions as a cytoplasmic component of the epithelial adherens junction belt, with a subcellular localization and tissue distribution and connects E-cadherin-p120 ctn complex to the microtubule cytoskeleton. It has been reported that PLEKHA7 acts as zonula adherens (ZA) component, identifies Nezha, which further binds to microtubules (MTs) of the cytoskeleton, and forms a protein complex during cytoskeleton assembly.
MONOCLONAL ANTI-PLEKHA7 ANTIBODY PRODUCED IN MOUSE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
