Fenofibrat
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- CAS-Nr.
- 49562-28-9
- Bezeichnung:
- Fenofibrat
- Englisch Name:
- Fenofibrate
- Synonyma:
- sedufen;Fenoglide;lf-178;lipsin;Lipirex;Liposit;Nolipax;Secalip;LIPYDIL;lipidax
- CBNumber:
- CB8266802
- Summenformel:
- C20H21ClO4
- Molgewicht:
- 360.83
- MOL-Datei:
- 49562-28-9.mol
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Fenofibrat Eigenschaften
- Schmelzpunkt:
- 80-810C
- Siedepunkt:
- 469.8±35.0 °C(Predicted)
- Dichte
- 1.177±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- L?slichkeit
- Practically insoluble in water, very soluble in methylene chloride, slightly soluble in ethanol (96 per cent)
- Aggregatzustand
- powder
- Farbe
- off-white
- Wasserl?slichkeit
- 0.8mg/L(25 ºC)
- Merck
- 14,3978
- BCS Class
- 2
- InChI
- InChI=1S/C20H21ClO4/c1-13(2)24-19(23)20(3,4)25-17-11-7-15(8-12-17)18(22)14-5-9-16(21)10-6-14/h5-13H,1-4H3
- InChIKey
- YMTINGFKWWXKFG-UHFFFAOYSA-N
- SMILES
- C(OC(C)C)(=O)C(OC1=CC=C(C(=O)C2=CC=C(Cl)C=C2)C=C1)(C)C
- EPA chemische Informationen
- Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester (49562-28-9)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
 
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H412 |
Sch?dlich für Wasserorganismen, mit langfristiger Wirkung. |
Langfristig (chronisch) gew?ssergef?hrdend |
Kategorie 3 |
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P273, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Fenofibrat Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R22:Gesundheitssch?dlich beim Verschlucken.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
Crystalline Solid
Verwenden
Fenofibrate has been used:
- to study its effect on plasma lipids, liver phenotype and gene expression
- to study its impact on endothelium-dependent vasodilatation of thoracic aorta
- to administer to NASH knock-in mice along with a high fat diet (HFD) to study its effect
Definition
ChEBI: A chlorobenzophenone that is (4-chlorophenyl)(phenyl)methanone substituted by a [2-methyl-1-oxo-1-(propan-2-yloxy)propan-2-yl]oxy group at position 1 on the phenyl ring.
Allgemeine Beschreibung
Fenofibrate, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoic acid 1-methylethyl ester (Tricor),has structural features represented in clofibrate. The primarydifference involves the second aromatic ring. This imparts agreater lipophilic character than exists in clofibrate, resultingin a much more potent hypocholesterolemic and triglycerideloweringagent. Also, this structural modification results in alower dose requirement than with clofibrate or gemfibrozil.
Fenofibrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Fenofibrat Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 715)Lieferanten
| Firmenname |
Telefon |
E-Mail |
Land |
Produktkatalog |
Edge Rate |
|
GIHI CHEMICALS CO.,LIMITED
|
+8618058761490
|
info@gihichemicals.com |
China |
49978 |
58 |
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Hebei Weibang Biotechnology Co., Ltd
|
+8615531157085
|
abby@weibangbio.com |
China |
8806 |
58 |
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Hebei Mujin Biotechnology Co.,Ltd
|
+86 13288715578 +8613288715578
|
sales@hbmojin.com |
China |
12830 |
58 |
|
Hebei Chuanghai Biotechnology Co,.LTD
|
+86-13131129325
|
sales1@chuanghaibio.com |
China |
5889 |
58 |
|
Sinoway Industrial co., ltd.
|
0592-5800732; +8613806035118
|
xie@china-sinoway.com |
China |
988 |
58 |
|
Nantong Guangyuan Chemicl Co,Ltd
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+undefined17712220823
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admin@guyunchem.com |
China |
615 |
58 |
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Shaanxi TNJONE Pharmaceutical Co., Ltd
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+8618092446649
|
sarah@tnjone.com |
China |
1143 |
58 |
|
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
|
+86-18600796368 +86-18600796368
|
sales@sjar-tech.com |
China |
484 |
58 |
|
Capot Chemical Co.,Ltd.
|
+86-（0）57185586718 +86-13336195806
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sales@capot.com |
China |
29793 |
60 |
|
Henan Tianfu Chemical Co.,Ltd.
|
+86-0371-55170693 +86-19937530512
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info@tianfuchem.com |
China |
21634 |
55 |
49562-28-9(Fenofibrat)Verwandte Suche:
- 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-propanoicaci1-methylethylester
- isopropyl(4’-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
- isopropyl2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
- lf-178
- lipantil
- procetofen
- proctofene
- Fenofibrate, >=99%
- 2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoic acid ethyl ester
- ethyl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate
- Propanoic acid, 2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-, ethyl ester
- 2-[4-(4-CHLOROBENZOYL)PHENOXYL-2-METHYLPROPANOIC ACID 1-METHYLETHYL ESTER
- 2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYL-PROPANOIC ACID, 1-METHYLETHYL ESTER
- 2-[4-(4-CHLOROBENZOYL)PHENOXY]-2-METHYLPROPANOIC ACID ISOPROPYL ESTER
- 2-[4-[p-Chlorobenzoyl]]-2-methylpropionic acid isopropyl ester
- Isopropyl 2-[p-[p-chlorobenzoyl] phenoxy]-2-methylpropionate
- Lipantyl
- Procetofene
- Lipidil Supra
- Lipirex
- Liposit
- MeltDose
- Nolipax
- NSC 281319
- Fenofibrite
- propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propanoate
- Elasterin
- Secalip
- 2-[p-(p-Chlorobenzoyl)phenoxy]-2-methylpropionic acid isopropyl ester
- LIPYDIL
- LIPANTHYL
- LABOTEST-BB LT00771982
- FENOFIBRATE
- 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-propionic acid isopropyl ester
- propan-2-yl 2-[4-(4-chlorophenyl)carbonylphenoxy]-2-methyl-propanoate
- Fenofibrate,2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoic acid isopropyl ester
- Fenofibrate (200 mg)
- Fenofibrate API
- Fenofibrate COS
- 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionic Acid Isopropyl Ester
Isopropyl 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropionate
- lipidax
- lipifen
- lipoclar
- lipofene
- lipsin
- Felodipine Solution, 100ppm
- Fenofibrate Solution, 1000ppm
- Fenobrate
- 2-[4-[(4-chlorophenyl)-oxomethyl]phenoxy]-2-methylpropanoic acid propan-2-yl ester
- Fenofibrate CRS
- Fenofibrate>
- Fenofibrate, 98%, reagent grade
- Lipanty
- Fenofibrate,>98%
- Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester
- Fenofibrate USP/EP/BP
- fat fenofibrat
- Lipofen
