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N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Struktur
1048038-90-9
CAS-Nr.
1048038-90-9
Englisch Name:
N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide
Synonyma:
COR167;N-(1-adamantyl)-6-isopropyl-4-oxo-1-pentyl-quinoline-3-carboxamide;N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide;N-((3s,5s,7s)-Adamantan-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide;3-Quinolinecarboxamide, 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
CBNumber:
CB82554246
Summenformel:
C28H38N2O2
Molgewicht:
434.61
MOL-Datei:
1048038-90-9.mol

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Eigenschaften

Dichte
1.15
L?slichkeit
DMF:5.0(Max Conc. mg/mL);11.5(Max Conc. mM)
Ethanol:3.0(Max Conc. mg/mL);6.9(Max Conc. mM)
Aggregatzustand
A crystalline solid

Sicherheit

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

SER-601 is a potent and selective peripheral cannabinoid (CB2) receptor agonist with 190-fold selectivity for CB2 over the central CB1 receptor (Kis = 6.3 and 1,220 nM, respectively). At 3 mg/kg, SER-601 has analgesic effects in a formalin-induced nocifensive study in mice without cannabis-like behavioral effects due to its low affinity for the CB1 receptor. SER-601 also has antidiabetic effects. Two to four week exposure to SER-601 ameliorates insulin resistance in vivo and increases insulin secretion and accumulation in pancreatic islets isolated from high-fat diet/streptozotocin (HFD/STZ)-induced diabetic mice.

Verwenden

SER-601 is a 4-quinolone-3-carboxylic acid derivative and a selective cannabinoid CB2 receptor agonist (1,2,3). It exhibits analgesic and neuroprotective properties.

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 16)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED 		+8618523575427
 sales@conier.com China 49732 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Jinan ponder chemical co. LTD 0531-0000
thinklifescience@163.com China 19689 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44813 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094
 marketing@targetmol.cn China 20032 58
Cayman Chemical Company 800-364-9897
sales@caymanchem.com China 27736 58
Enzo Biochem Inc Enzo Biochem Inc. 13797054060
 Enzoname@qq.com China 177174 58
Santa Cruz Biotechnology Inc 60936350
 scbt@scbt.com China 222068 58
  • N-(Adamant-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinolin-3-carboxamide
  • N-((3s,5s,7s)-Adamantan-1-yl)-6-isopropyl-4-oxo-1-pentyl-1,4-dihydroquinoline-3-carboxamide
  • N-(1-adamantyl)-6-isopropyl-4-oxo-1-pentyl-quinoline-3-carboxamide
  • 3-Quinolinecarboxamide, 1,4-dihydro-6-(1-methylethyl)-4-oxo-1-pentyl-N-tricyclo[3.3.1.13,7]dec-1-yl-
  • COR167
  • 1048038-90-9
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