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RUBRATOXINA

RUBRATOXINA Struktur
22467-31-8
CAS-Nr.
22467-31-8
Englisch Name:
RUBRATOXINA
Synonyma:
RUBRATOXINA;Rubratoxin A, PP2A inhibitor;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
CBNumber:
CB81405198
Summenformel:
C26H32O11
Molgewicht:
520.528
MOL-Datei:
22467-31-8.mol

RUBRATOXINA Eigenschaften

Schmelzpunkt:
210-214℃ (decomposition)
storage temp. 
Store at -20°C
L?slichkeit
Acetonitrile: soluble; DMSO: soluble
Aggregatzustand
A powder
Farbe
White

Sicherheit

Giftige Stoffe Daten 22467-31-8(Hazardous Substances Data)

RUBRATOXINA Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

Verwenden

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

RUBRATOXINA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


RUBRATOXINA Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 18)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207
sales@molcore.com China 49734 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Shanghai Tauto Biotech Co., Ltd. 021-51320588
tauto@tautobiotech.com China 3989 66
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 24644 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939
shenlinxing@macklin.cn China 30016 58
Chengdu Peter-like Biotechnology Co., Ltd. 028-81700200 13308200041
2851167782@qq.com China 11183 58
United States Biological --
sales@advtechind.com United States 6075 58

22467-31-8()Verwandte Suche:


  • RUBRATOXINA
  • 10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione
  • 9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride
  • 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
  • Rubratoxin A, PP2A inhibitor
  • 22467-31-8
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