Citrullinated Vimentin (human recombinant) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Vimentin is a cytoskeleton intermediate filament protein present in cells of mesenchymal origin, including leukocytes, endothelial cells, and smooth muscle cells. It is subject to citrullination by peptidyl arginine deiminase 2 (PAD2; ) under high calcium concentrations, which can occur during macrophage apoptosis. Citrullinated vimentin has been shown to have a role in the production of anti-citrullinated protein antibodies (ACPAs). ACPAs against citrullinated proteins, such as vimentin, are considered to be highly specific markers for rheumatoid arthritis and other autoimmune diseases.
Citrullinated Vimentin (human recombinant) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
