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NCT-501

NCT-501 Struktur
1802088-50-1
CAS-Nr.
1802088-50-1
Englisch Name:
NCT-501
Synonyma:
CS-2069;NCT-501;NCT-501 >=98% (HPLC);Inhibitor,Aldehyde Dehydrogenase (ALDH),inhibit,NCT-501,NCT 501;8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione;8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione , NCT-501;1H-Purine-2,6-dione, 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-
CBNumber:
CB73043300
Summenformel:
C21H32N6O3
Molgewicht:
416.52
MOL-Datei:
1802088-50-1.mol

NCT-501 Eigenschaften

Siedepunkt:
627.3±65.0 °C(Predicted)
Dichte
1.37±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
≥20.85 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥11 mg/mL in EtOH
Aggregatzustand
solid
pka
5.26±0.10(Predicted)
Farbe
White to off-white

Sicherheit

NCT-501 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

NCT-501 is a potent, reversible, theophylline-based inhibitor of ALDH1A1 (IC50 = 40 nM for the human form). It is selective for ALDH1A1 over other ALDH isozymes as well as other dehydrogenases. Pharmacokinetic studies indicate that NCT-501 has high bioavailability when delivered intraperitoneally, with rapid phase I modification in the liver.

NCT-501 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

NCT-501 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 82)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32956 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226
 sales@hzclap.com CHINA 6312 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.
support@targetmol.com United States 38631 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Dalian Meilun Biotech Co., Ltd. 0411-62910999 13889544652
 sales@meilune.com China 4727 58
Haoyuan Chemexpress Co., Ltd. 021-58950125
info@chemexpress.com China 7552 61
  • NCT-501
  • CS-2069
  • 1H-Purine-2,6-dione, 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-
  • NCT-501 >=98% (HPLC)
  • Inhibitor,Aldehyde Dehydrogenase (ALDH),inhibit,NCT-501,NCT 501
  • 8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
  • 8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione , NCT-501
  • 1802088-50-1
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