Gastrin I (1-14) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Gastrin I (1-14) has been used:
- as a component of gastric cancer stem/progenitor cell (GCSPC) medium for tumorsphere culture
- as a supplement in organoid growth medium (OGM) for patient-derived organoid (PDO)
- in viable lymphocytes culture for re-stimulation assay
Allgemeine Beschreibung
Gastrin, a classic digestive hormone, is found in three major forms: gastrin-34 (big gastrin), gastrin-17 (little gastrin), and gastrin-13 (minigastrin). Mammalian gastrin consists of a C-terminal four amino-acid sequence and a sulfated tyrosine 7 residue from the C-terminus. Gastrin is mostly found in the G cells of the stomach mucosa. Nutrients and gastrin-releasing peptides stimulate the release of gastrin.
Biochem/physiol Actions
Gastrin is a linear polypeptide that induces the secretion of gastric acid (HCl) by parietal cells.
Gastrin I (1-14) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
