Monoclonal Anti-Rabbit IgG (γ-chain specific) Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Monoclonal Anti-Rabbit IgG (γ-chain specific) antibody produced in mouse has been used in
- enzyme linked immunosorbent assay (ELISA)
- dot blots
- immunohistology
- western blotting
- peptide mass fingerprinting (PMF)
Allgemeine Beschreibung
Monoclonal Anti-Rabbit IgG (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. Immunoglobulins (Igs) belongs immunoglobulin super-family. There are five different types of immunoglobulins. Each immunoglobulin has two heavy (H) and two light (L), held together by disulphide linkages. Each light comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region.
Biochem/physiol Actions
Digestion of IgG by papain generates fragment antigen binding (Fab). Pepsin digestion of IgG results in fragment crystallisable (fc). IgG antibody has enormous therapeutic potential and the Fc region is involved in the development of therapeutic antibody.
Monoclonal Anti-Rabbit IgG (γ-chain specific) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
