Trypsinogen Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R42:Sensibilisierung durch Einatmen m?glich.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24:Berührung mit der Haut vermeiden.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.

Verwenden

Trypsinogen from bovine pancreas is suitable for use in:

• the secondary structure analysis of proteins in H2O solution using single-pass attenuated total reflection Fourier transform infrared (ATR-FT-IR) microscopy
• tuning and calibration of electrospray ionization quadrupole time-of-flight (ESI-Q-TOF) mass spectrometer
• the secondary structure analysis of proteins by infrared (IR) spectroscopy
• SDS-PAGE as a molecular weight standard (24kDa)

Allgemeine Beschreibung

Trypsinogen is a proenzyme (zymogen) that is activated to form trypsin. It is synthesized in the pancreas and activated by enterokinase once it reaches the lumen of the small intestine. Bovine trypsinogen is a single polypeptide chain of 229 amino acids that is cross linked by six disulfide bridges. Enterokinase cleaves a hexapeptide to from the NH₂ terminus of trypsinogen at the Lys6 - Ile7 peptide bond and activates it. Trypsin, thus formed, autocatalytically activates more trypsinogen to trypsin. This native form of trypsin is called β-trypsin, which undergoes autolysis at Lys₁₃₁ - Ser₁₃₂ resulting in α-trypsin that is held together by disulfide bridges. Trypsin is a serine protease with His₄₆ and Ser₁₈₃ at the active site. The pH optimum of trypsin is 7 - 9.

Biochem/physiol Actions

Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin.

Trypsinogen Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Trypsinogen Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Raw material medicin reagent co.,Ltd		sales@njromanme.com	China	4529	58
Beijing OKA biological technology co., LTD	010-010-010-62971590 18548936886	jack@oka-vip.com	China	6897	58
Shanghai Sig Biotechnology Co., LTD	021-57810052 18930344717	2089316240@qq.com	China	9395	58
Wuhan Yanzhe Technology Co., Ltd	15527250409	wenhaotian12@163.com	China	4169	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	17691182729 18161915376	1046@dideu.com	China	9993	58
Beijing Baileisen Biotechnology Co., Ltd.	13581502185	joe0415zhaxi@163.com	China	141	58

9002-08-8(Trypsinogen)Verwandte Suche:

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• TRYPSINOGEN
• trypsinogen from bovine pancreas
• TRYPSINOGEN FROM BEEF PANCREAS
• Trypsinogen, PMSF treated from bovine pancreas
• Trypsinogen >2500U/mg from bovine pancreas
• Trypsinogen >2500 U/mg from bovine
• Ttrypsinogen
• 9002-08-8
• Protein Analysis
• Proteases & Protein Sequencing
• Proteases
• Peptide and protein standards for mass spectrometry analysis
• Mass Spectrometry
• Enzymes, Inhibitors, and Substrates
• Proteomics and Protein Expression
• Application Index
• Biochemicals and Reagents
• BioChemical
• Auxiliary Proteins
• Other
• Proteins and Derivatives
• Peptide and protein standards for mass spectrometry analysisApplication Index
• Mass Spectrometry
• Proteases
• Proteases&Protein Sequencing
• Proteomics