3-Amino-4-methoxybenzanilid
|
|
|
- CAS-Nr.
- 120-35-4
- Bezeichnung:
- 3-Amino-4-methoxybenzanilid
- Englisch Name:
- 3-Amino-4-methoxybenzanilide
- Synonyma:
- AMBA;AMAN;Red KD Base;Red based KD;FAST RED KD BASE;3-AMINO-P-ANISANILIDE;LABOTEST-BB LT01138545;4-Methoxy-3-aminobenzanilide;3-AMINO-4-METHOXYBENZANILIDE;3-amino-4-methoxy-benzanilid
- CBNumber:
- CB7251074
- Summenformel:
- C14H14N2O2
- Molgewicht:
- 242.27
- MOL-Datei:
- 120-35-4.mol
|
3-Amino-4-methoxybenzanilid Eigenschaften
- Schmelzpunkt:
- 154-156°C
- Siedepunkt:
- 385.1°C (rough estimate)
- Dichte
- 1.1338 (rough estimate)
- Dampfdruck
- 0-0Pa at 25℃
- Brechungsindex
- 1.6419 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- L?slichkeit
- DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.44±0.70(Predicted)
- Farbe
- White to Off-White
- LogP
- 2.08 at 23℃ and pH7
- CAS Datenbank
- 120-35-4(CAS DataBase Reference)
- EPA chemische Informationen
- Benzamide, 3-amino-4-methoxy-N-phenyl- (120-35-4)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| R-S?tze: |
36/37/38 |
|
|
| S-S?tze: |
26-36/37/39 |
|
|
| RTECS-Nr. |
CV7400000 |
|
|
| TSCA |
Yes |
|
|
| HazardClass |
IRRITANT |
|
|
| HS Code |
2924297099 |
|
|
| Toxizit?t |
mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#01183, |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
|
3-Amino-4-methoxybenzanilid Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Gray powder.
Verwenden
Dyes, pharmaceuticals, and other organic chemicals.
Synthese
3-Amino-4-methoxybenzanilide is prepared by the reaction of 3-amino-4-methoxybenzoic acid and aniline. The steps are as follows:
A total of 0.17 mL (0.18 mmol) of DIC and 0.24 g (0.18 mmol) of HOBt were added to a dichloromethane solution of 0.20 g (0.12 mmol) of 1 at room temperature, and the reaction mixture was stirred for 0.5 h.
Then, 0.13 mL (0.14 mmol) of aniline was added to the mixture.
After approximately 3 h, 0.5 N NaOH was added to the solution.
The lower layer was isolated, and 0.5 N HCl was added until the aqueous solution was neutral.
The dichloromethane layer was washed three times with 10 mL of water, and then MgSO4 was added.
After 2 h, the solution was filtered, and the solvent was removed.
The residue was purified by column chromatography on silica gel (eluent: petroleum ether:ethyl acetate = 3:1) to yield the desired 3-Amino-4-methoxybenzanilide as a white solid (yield: 76%). Mp: 197-198 °C. 1H NMR (400 MHz, DMSO-d6) δ (ppm): 9.92 (1H, s, NH), 7.74 (2H, d, J = 9.0 Hz, PhH), 7.32 (2H, m, PhH), 7.21 (2H, d, J = 8.0 Hz, PhH), 7.06 (1H, m, PhH), 6.88 (1H, d, J = 8.0 Hz, PhH), 4.90 (2H, br s, NH2), 3.83 (3H, s, OCH3). ESI-MS (m/z): 243 (M + H)+.
3-Amino-4-methoxybenzanilid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
3-Amino-4-methoxybenzanilid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 272)Lieferanten
120-35-4(3-Amino-4-methoxybenzanilid)Verwandte Suche:
- AMAN
- AMBA
- 3-AMINO-4-METHOXYBENZANILIDE
- 3-AMINO-4-METHOXY-N'-PHENYL BENZAMIDE
- 3-AMINO-P-ANISANILIDE
- LABOTEST-BB LT01138545
- FAST RED KD BASE
- 3-Amino-p-anisanilide,prac.,95%
- N-(3-amino-4-methoxyphenyl)benzamide
- 4-Methoxy-3-aminobenzanilide
- N-Phenyl-4-methoxy-3-aminobenzamide
- 3-amino-4-methoxy-benzanilid
- 3-amino-4-methoxy-n-phenyl-benzamid
- 1-hydroxy-6,8a-dimethylspiro[4a,6,7,8-tetrahydro-4H-naphthalene-5,2'-oxirane]-1,2-dicarboxaldehyde
- Benzamide,3-amino-4-methoxy-N-phenyl-
- 3-Amino-4-methoxybenzanilide >
- Red KD Base
- 3-Amino-4-methoxybenzanilide ISO 9001：2015 REACH
- DB-40 (3-AMINO-4-METHOXYBENZANILIDE )
- 3-Amino-4-methoxybenzanilide 120-35-4
- Red based KD
- 120-35-4
- Intermediates of Dyes and Pigments
- Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
