Dolutegravir 2-Desfluoro Impurity

1863916-88-4

CAS-Nr.: 1863916-88-4

Englisch Name:: Dolutegravir 2-Desfluoro Impurity

Synonyma:: 4-Fluoro Dolutegravir;Dolutegravir Impurity G;Dolutegravir Impurity 50;Dolutegravir Impurity 47;Dolutegravir 4-Fluoro Impurity;Dolutegravir 2-Desfluoro Impurity;(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-;2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity;Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide

CBNumber:: CB64796145

Summenformel:: C20H20FN3O5

Molgewicht:: 401.39

MOL-Datei:: 1863916-88-4.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 32

Dolutegravir 2-Desfluoro Impurity Eigenschaften

Siedepunkt:: 675.7±55.0 °C(Predicted)

Dichte: 1.49±0.1 g/cm3(Predicted)

L?slichkeit: DMSO (Slightly), Methanol (Slightly, Heated)

Aggregatzustand: Solid

pka: 4.50±1.00(Predicted)

Farbe: Off-White to Light Brown

Sicherheit

Dolutegravir 2-Desfluoro Impurity Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 2-Desfluoro Impurity Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Dolutegravir 2-Desfluoro Impurity Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 32)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8647	58
sgtlifesciences pvt ltd	+8617013299288	dj@sgtlifesciences.com	China	12373	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11922	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3389	58
Moxin Chemicals	+8617320513646	mike@molcoo.com	China	9558	58
Shenzhen Roark Pharma-Tec Co., Ltd.	13128912434	2880126944@qq.com	China	2577	58
Beijing Comparison Pharmaceutical Technology Co., Ltd	010-010-52878169 15801002657	sales@bjcomparison.com	China	4717	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18070	56
Shanghai CR Corporation Limited	021-80270511; 4006653949	fred.wen@crcorporation.cn	China	10044	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1130	58

2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-/Dolutegravir impurity
Dolutegravir impurity 4/Defluoro Dolutegravir/(4R,12aS)-N-(4-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity G
Dolutegravir 2-Desfluoro Impurity
2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(4-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)-
(4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide
Dolutegravir Impurity 47
Dolutegravir Impurity 50
4-Fluoro Dolutegravir
Dolutegravir 4-Fluoro Impurity
1863916-88-4

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