Anti-transcription factor 21 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-TCF21 antibody produced in rabbit has been used in:
- immunofluorescence
- flow cytometry
- chromatin immunoprecipitation
Allgemeine Beschreibung
Transcription factor TCF21 (TCF21) or capsulin, expressed in proepicardial cells is mapped to human chromosome 6q23.2.
Biochem/physiol Actions
Transcription factor TCF21 (TCF21) regulates mesenchymal-to-epithelial differentiation and smooth muscle cells (SMCs) phenotypic modulation. The deletion of TCF21 gene leads to SMC upregulation. Hypermethylation of TCF21 is implicated in non-small cell lung cancer (NSCLC). TCF21 is a tumor suppressor and is involved in the invasion and metastasis. Elevated expression of TCF21 leads to hepatocellular cancer suppression. It also elicits anti-angiogenic activity in cholangiocarcinoma. TCF21 locus is also associated with coronary heart disease(CAD).
Anti-transcription factor 21 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
