Viomycin
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- CAS-Nr.
- 32988-50-4
- Bezeichnung:
- Viomycin
- Englisch Name:
- viomycin
- Synonyma:
- Viocin;viomycin;Vioactane;Coliomycin;FLORIMYCIN;Vinacetin A;Tuberactinomycin B;viomycin USP/EP/BP;Glycine, 3-amino-N-[(3S)-3,6-diamino-1-oxohexyl]-L-alanyl-L-seryl-L-seryl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-2-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-, (5→13)-lactam, (2S)-;(S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamidedisulfate
- CBNumber:
- CB5910382
- Summenformel:
- C25H43N13O10
- Molgewicht:
- 685.7
- MOL-Datei:
- 32988-50-4.mol
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Viomycin Eigenschaften
- Schmelzpunkt:
- 280 °C
- Siedepunkt:
- 695.81°C (rough estimate)
- Dichte
- 1.3613 (rough estimate)
- Brechungsindex
- 1.6700 (estimate)
- storage temp.
- Store at -20°C
- L?slichkeit
- Water (Slightly)
- Aggregatzustand
- Powder
- pka
- pKa 8.2 (Uncertain);10.3 (Uncertain)
- Wasserl?slichkeit
- Soluble to 75 mM in water
- Stabilit?t:
- Hygroscopic
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
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| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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Viomycin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Viomycin was found independently in 1951, in the culture broth of Streptomyces puniceus by Pfizer Research Laboratories and in that of S. floridae by Parke Davis Co. It shows strong activity against Mycobacterium species and moderate activity against gram-positive and gram-negative bacteria. Viomycin has been used by intramuscular administration to treat tuberculosis, but because of its ototoxicity and renal toxicity it is being replaced by more active and less toxic drugs, such as enviomycin and other antituberculotic antibiotics.
Indications
Viomycin is a complex polypeptide antibiotic that is active
against MDR strains of tuberculosis. Cross-resistance
between viomycin and kanamycin is less frequent
than between viomycin and capreomycin.
Definition
ChEBI: A cyclic peptide antibiotic produced by the actinomycete Streptomyces puniceus, used in the treatment of tuberculosis.
Biologische Aktivit?t
Member of the tuberactinomycin family of antibiotics . Inhibits group I intron splicing and prokaryotic protein synthesis. Freezes bacterial ribosomes in either the pre- or post-translational state. Facilitates trans -cleavage of the Neurospora VS ribozyme.
Viomycin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Viomycin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 16)Lieferanten
32988-50-4(Viomycin)Verwandte Suche:
- viomycin
- FLORIMYCIN
- Coliomycin
- Tuberactinomycin B
- Vinacetin A
- Vioactane
- Viocin
- (S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamidedisulfate
- Glycine, 3-amino-N-[(3S)-3,6-diamino-1-oxohexyl]-L-alanyl-L-seryl-L-seryl-(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-2-[(4R,6S)-2-amino-1,4,5,6-tetrahydro-6-hydroxy-4-pyrimidinyl]-, (5→13)-lactam, (2S)-
- viomycin USP/EP/BP
- 32988-50-4
- C25H43N13O10
- C25H43N13O102H2SO4
