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CP-154,526

CP-154,526 Struktur
157286-86-7
CAS-Nr.
157286-86-7
Englisch Name:
CP-154,526
Synonyma:
CP154;CP 154;CP-154;CP-154,526;N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-;N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride
CBNumber:
CB5675292
Summenformel:
C23H32N4
Molgewicht:
364.53
MOL-Datei:
157286-86-7.mol

CP-154,526 Eigenschaften

Siedepunkt:
423.5±45.0 °C(Predicted)
Dichte
1.06
storage temp. 
Desiccate at +4°C
pka
6.97±0.30(Predicted)

Sicherheit

CP-154,526 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.

Biologische Aktivit?t

Selective, non-peptide CRF 1 receptor antagonist (K i values are 2.7 and > 10000 nM for CRF 1 and CRF 2 receptors respectively). Blocks CRF-induced adenylate cyclase activation (K i = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.

CP-154,526 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CP-154,526 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 22)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19881 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
LETOPHARM LIMITED +86-21-5821 5861
sales@letopharm.com China 2384 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761
 486064515@qq.com China 4996 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24644 58
  • N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
  • 7H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-
  • CP-154,526
  • N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride
  • CP-154
  • CP154
  • CP 154
  • N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
  • 157286-86-7
  • C23H32N4HCl
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Neurochemicals
  • Pfizer Compounds
  • Pharmaceuticals
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