Erythromycinlactobionat Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including
Streptococcus,
Staphylococcus, and
Haemophilus (MIC
90s range from 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications. Erythromycin lactobionate is a soluble salt of erythromycin that is typically used for intraperitoneal or intravenous injections.
Chemische Eigenschaften
White or slightly yellow hygroscopic, powder.
Verwenden
Macrolide antibacterial.
Allgemeine Beschreibung
Erythromycin lactobionate is a water-soluble salt preparedby reacting erythromycin base with lactobiono-σ-lactone. Itoccurs as an amorphous powder that is freely soluble inwater and alcohol and slightly soluble in ether. It is intended,after reconstitution in sterile water, for intravenousadministration to achieve high plasma levels in the treatmentof serious infections.
Erythromycinlactobionat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte