dsDNA Monoclonal Antibody (Clone 2C4) Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
In response to stimuli, neutrophils have the ability to release net-
like structures containing nuclear DNA, de-
condensed histones, and antimicrobial peptides. These neutrophil extracellular traps (NETs) have the ability to contact and kill pathogens including fungi, bacteria, and protozoa; they are then rapidly cleared by the immune system. However, in aged NZBWF1 mice and human lupus patients, the clearance is delayed, allowing formation of antibodies to these NET components. Cayman’s dsDNA Monoclonal Antibody was developed by fusing the spleen of a non-
immunized NZBWF1 mouse with a mouse myeloma cell line. It detects dsDNA by ELISA and can be used to stain NETs by immunofluorescence.
dsDNA Monoclonal Antibody (Clone 2C4) Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
