1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH exhibiting a K_i value of 0.57 nM. Using a proteonomics approach, CAY10435 was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, CAY10435 exhibited IC₅₀ values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of CAY10435 obtained from this experiment should allow for more accurate interpretation of results using the inhibitor in complex environments such as whole cells or animals.

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6777	58
Suzhou Zhixin Biotechnology Co., Ltd.	0512-65118909 15162312715	sales@szzxbio.com	China	2991	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19699	58

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• CAY10435
• 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
• 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
• 1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-
• 288862-73-7