1,2-Epoxybutan Chemische Eigenschaften,Einsatz,Produktion Methoden
ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die D?mpfe sind schwerer als Luft und k?nnen sich am Boden ausbreiten. Fernzündung m?glich. Die D?mpfe mischen sich leicht mit Luft. Bildung explosionsf?higer Gemische. Flie?en, Schütten o.?. kann zu elektrostatischer Aufladung führen.
CHEMISCHE GEFAHREN
Kann polymerisieren bei Kontakt mit S?uren, Alkalien, Zinn, Aluminium und Eisenchloriden unter Feuer- und Explosionsgefahr. Reagiert mit starken Oxidationsmitteln unter Feuergefahr.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: Hautresorption; Krebserzeugend Kategorie 2; (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den K?rper durch Inhalation der D?mpfe, über die Haut und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitssch?dliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION: Die Substanz reizt die Augen, die Haut und die Atemwege. Exposition gegenüber hohen Konzentrationen kann Bewusstseinstrübung verursachen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
M?glich sind Auswirkungen auf das Nervensystem. M?glicherweise krebserzeugend für den Menschen.
LECKAGE
Gefahrenbereich verlassen bei gro?en Mengen! Ausgelaufene Flüssigkeit in abdichtbaren Beh?ltern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Kanalisation spülen. Pers?nliche Schutzausrüstung: Atemschutzfilter für organische D?mpfe niedrigsiedender Verbindungen.
R-S?tze Betriebsanweisung:
R11:Leichtentzündlich.
R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
R40:Verdacht auf krebserzeugende Wirkung.
R52/53:Sch?dlich für Wasserorganismen, kann in Gew?ssern l?ngerfristig sch?dliche Wirkungen haben.
S-S?tze Betriebsanweisung:
S9:Beh?lter an einem gut gelüfteten Ort aufbewahren.
S16:Von Zündquellen fernhalten - Nicht rauchen.
S29:Nicht in die Kanalisation gelangen lassen.
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Chemische Eigenschaften
1,2-Butylene oxide is a colorless mobile liquid with an unpleasant smell. This low boiling liquid has but limited water solubility, yet is miscible with most common organic solvents. It undergoes the usual reactions of epoxides with compounds having labile hydrogen atoms. Some of these are acids, amines, ammonia, alcohols, phenols, polyols, thiols, etc. Butylene oxide can be polymerized or copolymerized with other alkylene oxides to yield polyethers. The resulting polymers are less water soluble than the polymers made from ethylene and propylene oxide, of equivalent chain length.
Verwenden
Intermediate for various polymers, stabilizer for
chlorinated solvents.
Allgemeine Beschreibung
A clear colorless volatile liquid with an ethereal odor. Flash point near 0°F. Density about 6.9 lb / gal. Soluble in water. Boiling point near 140°F. Flammable over a wide range of vapor-air concentrations. May polymerize with the evolution of heat and possible rupture of container if contaminated. Vapors irritate eyes, skin and respiratory system. Prolonged contact with skin may cause in delayed burns. Vapors are heavier than air. Used as an intermediate to make various polymers. Chemicals that polymerize are often stabilized by refrigeration.
Air & Water Reaktionen
Highly flammable. Soluble in water and may decompose upon contact with water.
Reaktivit?t anzeigen
Epoxides, such as 1,2-EPOXYBUTANE, are highly reactive. They polymerize in the presence of catalysts or when heated. Contact with anhydrous metal halides; amino, hydroxyl and carboxyl functions; inorganic acids and charcoal may cause polymerization. These polymerization reactions can be violent. Compounds in this group react with acids, bases, and oxidizing and reducing agents. They react, possibly violently with water in the presence of acid and other catalysts.
Hazard
Toxic concentration of vapors occurs at
room temperature. Highly flammable, dangerous
fire risk. Possible carcinogen.
Health Hazard
Inhalation: intolerable odor and irritation; respiratory injury may occur at higher levels. Ingestion causes irritation of mouth and stomach. Contact with either liquid or vapor may cause burns of eyes. Liquid produces frostbite-type of skin burn if free to evaporate; if confined to skin, burn may cause skin sensitization; not readily absorbed in toxic amounts.
Brandgefahr
Behavior in Fire: Containers may explode in fire. Use water to cool container from safe distance.
Sicherheitsprofil
Confirmed carcinogen
with experimental carcinogenic data.
Moderately toxic by ingestion and skin
contact. Mtldly toxic by inhalation.
Experimental reproductive effects. Mutation
data reported. Dangerous fire hazard when
exposed to heat, flame, or powerful
oxidizers. To fight fire, use dry chemical,
water spray, mist or fog, alcohol foam.
When heated to decomposition it emits
acrid smoke and fumes.
m?gliche Exposition
It is used as a stabilizer in chlorinated
solvents, and to make other chemicals, such as gasoline
additives.
Carcinogenicity
Exposure to 1000 ppm before and during
gestation did not cause any teratogenic effects
in rats; fetal growth and viability were not
affected despite depressed maternal body
weight gain.6 Rabbits exposed at 250 or
1000ppm 7 hours/day during gestational days
0 to 24 had maternal deaths at both exposure
concentrations. No teratogenic effects were
observed, although the pregnancy rate was
reduced in the high-dose group. 1,2-Epoxybutane
is a direct-acting alkylating agent, and it is
genotoxic in a wide range of assays.
Instilled in the eyes of rabbits, 1,2-
epoxybutane caused corneal injury.
A threshold limit value (TLV) has not been
established for 1,2-epoxybutane, although US
manufacturers have recommended a voluntary
time-weighted average-threshold limit value of
40ppm.
Versand/Shipping
UN3022 1,2-Butylene oxide, stabilized, Hazard
Class: 3; Labels: 3—Flammable liquid
l?uterung methode
Dry it with CaSO4, and fractionally distil it through a long (126cm) glass helices-packed column. The first fraction contains a water azeotrope. [Beilstein 17 II 17.]
Inkompatibilit?ten
May form explosive mixture with air.
Unless inhibited, can form unstable and explosive peroxides. Before entering confined space where this chemical
may be present, check to make sure that an explosive concentration does not exist. Polymerization will occur in the
presence of acids, strong bases and chlorides of tin, iron and
aluminum. Storage tanks and other equipment should be
absolutely dry and free from air, ammonia, acetylene,
hydrogen sulfide, rust and other contaminants. Incompatible
with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline
materials, strong bases, strong acids, oxoacids, epoxides.
Attacks some plastics. May accumulate static electric
charges that can result in ignition of its vapors. A regulated,
marked area should be established where this chemical is
handled, used, or stored in compliance with OSHA Standard
1910.1045.
1,2-Epoxybutan Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
