(Z)-2-Methyl-2-butenoic acid [(1S,2R,7aR)-hexahydro-2β-hydroxy-1H-pyrrolizin-1β-yl]methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
A pyrrolizidine alkaloid, macrophylline has been isolated from Senecio amphibolus
and S. macrophylla MB. It forms a low melting solid which has not yet been
obtained in a crystalline form. The base is dextrorotatory having a specific rotation
of [α]
20D + 34.52° (c 1.68, EtOH). When hydrolyzed with dilute acids the base
furnishes macronecine and angelic acid. It has been characterized as the crystalline
bitartrate which melts at 162-4°C.
Einzelnachweise
Danilova et al.,J. Gen. Chem. USSR, 23,1417 (1953)
Danilova, Kuzovkov, ibid, 23,1597 (1953)
Danilova, Utkin, Massagetov, ibid, 25, 797 (1955)
Danilova, Utkin, ibid, 30, 345 (1960)
Culvenor, Geissman,J. Org. Chem., 26, 3045 (1961)
(Z)-2-Methyl-2-butenoic acid [(1S,2R,7aR)-hexahydro-2β-hydroxy-1H-pyrrolizin-1β-yl]methyl ester Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte