Cefprozil
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Cefprozil Eigenschaften
- Schmelzpunkt:
- 215-217°C (dec.)
- Siedepunkt:
- 803℃
- Dichte
- 1.53±0.1 g/cm3(Predicted)
- RTECS-Nr.
- XI0339000
- Flammpunkt:
- >110°(230°F)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- L?slichkeit
- DMF: 0.3 mg/ml; DMSO: 2.5 mg/ml; PBS (pH 7.2): 1.25 mg/ml
- Aggregatzustand
- Powder
- pka
- 2.92±0.50(Predicted)
- Wasserl?slichkeit
- Soluble in DMSO at 10mg/ml. Insoluble in water.
- BCS Class
- 3
- InChIKey
- WDLWHQDACQUCJR-PBFPGSCMSA-N
- SMILES
- N12[C@@]([H])([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C1=O)SCC(C=CC)=C2C(O)=O
- CAS Datenbank
- 92665-29-7(CAS DataBase Reference)
Sicherheit
Cefprozil Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Cefprozil is a new orally active cephalosporin useful in the treatment of otitis media, uncomplicated skin and skin structure infections plus upper/lower respiratory tract infections. Although structurally similar to cefadroxil, its spectrum of antibacterial activity is comparable to cefaclor, but exhibits greater activity against S.aureus, S. epidermidis, Listeria monocytogenes, Streptococci, H. influenzae, Propionibacterium acnes. Clostridium perfringens and difficile.Chemische Eigenschaften
Pale Yellow SolidVerwenden
Semisynthetic oral cephalosporin consisting of approx. 90:10 Z/E isomeric mixture. AntibacterialDefinition
ChEBI: A semisynthetic, second-generation cephalosporin, with prop-1-enyl and (R)-2-amino-2-(4-hydroxyphenyl)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used to treat bronchitis as well as ear, skin and other bacterial infec ions.Antimicrobial activity
Activity against Gram-positive cocci and Gram-negative bacilli is better than that of cefadroxil (which it structurally resembles) but is not as good as that of group 5 agents . It is moderately stable to hydrolysis by the common plasmid-mediated β-lactamases, but is hydrolyzed by the chromosomal enzymes of Gram-negative bacilli .Hazard
Moderately toxic by ingestion. Human sys- temic effects.Clinical Use
Cefprozil (Cefzil) is an orally active second-generationcephalosporin that is similar in structure and antibacterialspectrum to cefadroxil. Oral absorption is excellent (oralbioavailability is about 95%) and is not affected by antacidsor histamine H2-antagonists. Cefprozil exhibits greater invitro activity against streptococci, Neisseria spp., and S. aureusthan does cefadroxil. It is also more active than thefirst-generation cephalosporins against members of theEnterobacteriaceae family, such as E. coli, Klebsiella spp., P. mirabilis, and Citrobacter spp. The plasma half-life of1.2 to 1.4 hours permits twice-a-day dosing for the treatmentof most community-acquired respiratory and urinary tractinfections caused by susceptible organisms.Nebenwirkungen
It is well tolerated. Diarrhea and gastrointestinal discomfort may occur. There have been a few reports of pseudomembranous colitis and serum sickness-like reactions.Cefprozil Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Cefprozil Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 283)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Lewoo Pharmatech(Shanghai)Co.,Ltd | +86-15800805830 +86-15800805830 |
miao@lewoopharma.com.cn | China | 184 | 58 |
Shenzhen Excellent Biomedical Technology Co.,Ltd. | +86-0755-26050679 +86-15915472436 |
sale@ex-biotech.cn | China | 1031 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 |
abby@weibangbio.com | China | 8806 | 58 |
Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12830 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
sarah@tnjone.com | China | 1143 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29879 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
Hebei Runbin Biotechnology Co. LTD | 13180553332 |
2179877681@qq.com | CHINA | 990 | 58 |
92665-29-7()Verwandte Suche:
2,4-Pentandion
Betain
Aminotransferase, Alanin-
3,4'-DIAMINODIPHENYLMETHANE
Paracetamol
Glycin
Acetylchlorid
Sulfamidsure
ALTRENOGEST
Glucosamin
Phenylaceton
TRIS EDTA ACETATE BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY
AMINO ACIDS
- (6R,7R)-7-[(2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYLAMINO]-8-OXO-3-(1-PRO-PENYL)-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
- Cefrozil
- K690 Cefprozil
- CEFPROZIL
- bmy28100
- (6r-(6-alpha,7beta(r*)))-l)acetyl)amino)-8-oxo-3-(1-propenyl)
- Cefprozil-d4
- (6R,7R)-7-[(2R)-2-aMino-2-(4-hydroxyphenyl)acetaMido]-8-oxo-3-[(1E)-prop-1-en-1-yl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- cis-Cefprozil
- (6R,7R)-7-[(R)-2-Amino-2-(p-hydroxyphenyl)acetylamino]-8-oxo-3-(1-propenyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 8-[2-Amino-2-(4-hydroxyphenyl)-acetyl]amino-7-oxo-4-prop-1-enyl-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid
- CEFPROZIL:(6R,7R)-7-[(2R)-2-AMINO-2-(4-HYDROXYPHENYL)ACETYLAMINO]-8-OXO-3-(1-PRO-PENYL)-5-THIA-1-AZABICYLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID
- (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-(1-propen-1-yl)-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
- Cefprozile
- Cephprozyl
- Procef
- Prozef
- 5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 7-(2R)-amino(4-hydroxyphenyl)acetylamino-8-oxo-3-(1-propenyl)-, (6R,7R)-
- (6R,7R)-7-[(2R)-2-Amino-2-(4-hydroxyphenyl) acetylamino]-8-oxo-3-(1-pro-penyl)-5-thia-1-azabicylo [4.2.0]oct-2-ene-2-carboxylic acid
- (6R-(6alpha,7beta(R*)))-7-((Amino(4-hydroxyphenyl)acetyl)amino)-8-oxo-3-(1-propenyl)-5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- (6S,7R)-7-((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-8-oxo-3-((E)-prop-1-en-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-(1-propen-1-yl)-, (6R,7R)-
- Cefprozil USP/EP/BP
- Cefprozil DISCONTINUED. Please see C243933.
- Cefprozi
- Cefprozil (Mixture of E,Z isomers)Q: What is Cefprozil (Mixture of E,Z isomers) Q: What is the CAS Number of Cefprozil (Mixture of E,Z isomers) Q: What is the storage condition of Cefprozil (Mixture of E,Z isomers) Q: What are the applications of Cefprozil (Mixture of E,Z isomers)
- (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)-1-oxoethyl]amino]-8-oxo-3-[(Z)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Cefprozil - mix of Z (92%), and E (7%) isomers
- Cefazolin propylene
- Cefprozil (BMY-28100)
- 92665-29-7
- 156-1-46
- 99-0-2
- C18H19N3SH2O
- C18H19N3O5S
- API
- cephalosporins
- Aromatics
- Heterocycles
- Sulfur & Selenium Compounds
- Intermediates & Fine Chemicals
- Pharmaceuticals