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6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride

6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride Struktur
850918-91-1
CAS-Nr.
850918-91-1
Englisch Name:
6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride
Synonyma:
Palbociclib Impurity 31 HCl;N-Methyl Palbociclib Hydrochloride;6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride
CBNumber:
CB45519903
Summenformel:
C25H32ClN7O2
Molgewicht:
498.03
MOL-Datei:
850918-91-1.mol

6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride Eigenschaften

Schmelzpunkt:
>186°C (dec.)
storage temp. 
Hygroscopic, Refrigerator, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Farbe
Pale Yellow to Light Yellow
Stabilit?t:
Hygroscopic

Sicherheit

6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

N-Methyl Palbociclib Hydrochloride is an impurity of Palbociclib (P139900), a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6 which may be useful in the treatment of breast cancer.

6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 6-acetyl-8-cyclopentyl-5-methyl-2-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride
  • Palbociclib Impurity 31 HCl
  • N-Methyl Palbociclib Hydrochloride
  • 850918-91-1
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