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CGP 20712 A

CGP 20712 A Struktur
105737-62-0
CAS-Nr.
105737-62-0
Englisch Name:
CGP 20712 A
Synonyma:
CGP207122HCl;CGP 20712 mesylate;CGP 20712 DIHYDROCHLORIDE;CGP-20712A methanesulfonate salt;CGP 20712A METHANESULFONATE SELECTIVE B1 ADRENOCE;CGP-20712A methanesulfonate salt solid, >=98% (HPLC);1-(2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino)-3-(4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy)-2-propanoldihyd;1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazoyl)phenoxy]-2-propanol mesylate;1-[2-((3-CARBAMOYL-4-HYDROXY)PHENOXY)ETHYLAMINO]-3-[4-(1-METHYL-4-TRIFLUOROMETHYL-2-IMIDAZOLYL)PHENOXY]-2-PROPANOL DIHYDROCHLORIDE;(+/-)-1-(2-(3-carbamoyl-4-hydroxyphenoxy)ethylamino)-3-(4-(1-methyl-4-trifluoromethyl-2-imidazolyl)-phenoxy)-2-propanol methane sulfonate
CBNumber:
CB4380786
Summenformel:
C24H29F3N4O8S
Molgewicht:
590.57
MOL-Datei:
105737-62-0.mol

CGP 20712 A Eigenschaften

storage temp. 
2-8°C
L?slichkeit
H2O: 10 mg/mL
Aggregatzustand
solid
Farbe
white

Sicherheit

WGK Germany  3

CGP 20712 A Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

CGP-20712A methanesulfonate salt has been used as a β1-adrenergic receptor antagonist in adult rat ventricular myocytes (ARVM) and rat cardiac fibroblasts. It may also be used as an antagonist for the β1-adrenergic receptor in rat bladder smooth muscles.

Biologische Aktivit?t

Highly selective and potent β 1 -adrenoceptor antagonist (IC 50 = 0.7 nM). Displays 10,000-fold selectivity over β 2 -adrenoceptors. Also available as part of the β -Adrenoceptor Antagonist Tocriset™ .

Biochem/physiol Actions

CGP-20712A methanesulfonate salt is a selective β1-adrenoceptor antagonist.

CGP 20712 A Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

CGP 20712 A Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 25)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
HBCChem, Inc. +1-510-219-6317
sales@hbcchem.com United States 10648 60
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686
 sales@rechemscience.com China 2998 58
DC Chemicals 021-58447131 13564518121
 sales@dcchemicals.com China 9409 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988968278
 sales@ubiochem.com China 4297 58
Nanjing Shizhou Biotechnology Co., Ltd 025-85563444 15850508050
 rose.shi@synzest.com China 269 58
Energy Chemical 021-58432009 400-005-6266
 marketing1@energy-chemical.com China 44807 58
cjbscvictory 13348960310 13348960310
 3003867561@qq.com China 10525 58
  • CGP 20712A METHANESULFONATE SELECTIVE B1 ADRENOCE
  • 1-(2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino)-3-(4-(1-methyl-4-trifluoromethyl-2-imidazolyl)phenoxy)-2-propanoldihyd
  • CGP207122HCl
  • CGP-20712A methanesulfonate salt
  • (±)-2-Hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl] amino]ethoxy]-benzamide methanesulfonate salt
  • 1-[2-((3-CARBAMOYL-4-HYDROXY)PHENOXY)ETHYLAMINO]-3-[4-(1-METHYL-4-TRIFLUOROMETHYL-2-IMIDAZOLYL)PHENOXY]-2-PROPANOL DIHYDROCHLORIDE
  • CGP 20712 DIHYDROCHLORIDE
  • CGP 20712 mesylate
  • 1-[2-((3-Carbamoyl-4-hydroxy)phenoxy)ethylamino]-3-[4-(1-methyl-4-trifluoromethyl-2-imidazoyl)phenoxy]-2-propanol mesylate
  • (+/-)-1-(2-(3-carbamoyl-4-hydroxyphenoxy)ethylamino)-3-(4-(1-methyl-4-trifluoromethyl-2-imidazolyl)-phenoxy)-2-propanol methane sulfonate
  • CGP-20712A methanesulfonate salt solid, >=98% (HPLC)
  • 105737-62-0
  • C23H25F3N4O5CH4O3S
  • C23H25F3N4O52HCl
  • C24H27F3N4O7S
  • Adrenoceptor
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