Anti-MGC133047
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- CAS-Nr.
- Englisch Name:
- Anti-MGC133047
- Synonyma:
- Anti-Hlcd;Anti-IFIH1;Anti-IDDM19;Anti-MGC133047;Anti-IFIH1 antibody produced in rabbit;Anti-MDA-5 antibody produced in rabbit;Anti-MDA5/IFIH1 antibody produced in goat;Anti-Helicard antibody produced in rabbit;Anti-Melanoma differentiation-associated protein 5;Anti-Interferon-induced with helicase C domain protein 1
- CBNumber:
- CB42905978
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Anti-MGC133047 Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- buffered aqueous solution
- Biologische Quelle
- rabbit
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Anti-MGC133047 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-MDA5 antibody produced in rabbit has been used in western blot analysis.
Allgemeine Beschreibung
Melanoma differentiation-associated protein 5 (MDA5), also known as interferon induced with helicase C domain 1 (IFIH1), is a cytosolic RNA sensor. It is encoded by the gene mapped to human chromosome 2q24.2. The encoded protein is a member of the retinoic acid-inducible gene I-like receptor family. MDA5 is characterized with both caspase recruitment domain and putative DExH group RNA helicase domains.
Biochem/physiol Actions
Melanoma differentiation-associated protein 5 (MDA5) plays a vital role in antiviral innate immune responses. In addition, the encoded protein also activates interferon regulatory factors 3 and 7 and nuclear factor-κB (NF-κB) via a mitochondrial viral signaling protein, inducing antiviral and proapoptotic responses, which is associated with various autoimmune diseases, such as type 1 diabetes (T1D), Graves′ disease (GD), multiple sclerosis (MS), psoriasis and rheumatoid arthritis (RA). Polymorphism in the gene is associated with the development of generalized vitiligo (GV).
Anti-MGC133047 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Anti-MGC133047 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 4)Lieferanten
- Anti-Hlcd
- Anti-IDDM19
- Anti-MDA5/IFIH1 antibody produced in goat
- Anti-MGC133047
- Anti-IFIH1
- Anti-Interferon-induced with helicase C domain protein 1
- Anti-Melanoma differentiation-associated protein 5
- Anti-IFIH1 antibody produced in rabbit
- Anti-Helicard antibody produced in rabbit
- Anti-Helicase with 2 CARD domains antibody produced in rabbit
- Anti-Interferon-induced helicase C domain-containing protein 1 antibody produced in rabbit
- Anti-Interferon-induced with helicase C domain protein 1 antibody produced in rabbit
- Anti-MDA-5 antibody produced in rabbit
- Anti-Melanoma differentiation-associated protein 5 antibody produced in rabbit
- Anti-RNA helicase-DEAD box protein 1 antibody produced in rabbit
