Anti-Myotonic dystrophy protein kinase-like beta Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
Allgemeine Beschreibung
CDC42BPB (CDC42 binding protein kinase beta, DMPK-like) is a 190kDa multi-domain protein belonging to the subfamily of Rho GTPase activated serine/threonine kinases within the AGC-family. AGC family members mainly support the actomyosin cytoskeleton assembly. It is expressed in a wide range of tissues.
Biochem/physiol Actions
CDC42BPB (CDC42 binding protein kinase beta, DMPK-like) plays a vital role in the regulation of tumor cell invasion. During cytoskeleton assembly, it influences cell shape and motility by facilitating the phosphorylation of myosin light chain (MLC).
Anti-Myotonic dystrophy protein kinase-like beta Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
