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6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Struktur
873436-91-0
CAS-Nr.
873436-91-0
Englisch Name:
6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
Synonyma:
CS-105;PU-H 71;NSC 750424;PU-H71 XHBr;PU-H71, >=98%;Zelavespib (PU-H71);PU-H71, 10 mM in DMSO;PU-H71 Trifluoroacetic Acid;9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine;8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine
CBNumber:
CB42554288
Summenformel:
C18H21IN6O2S
Molgewicht:
512.37
MOL-Datei:
873436-91-0.mol

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Eigenschaften

Schmelzpunkt:
>194oC (dec.)
Siedepunkt:
650.6±65.0 °C(Predicted)
Dichte
1.84
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
L?slichkeit
DMSO (Slightly), Methanol (Slightly)
pka
10.16±0.29(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Pale Beige

Sicherheit

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Trifluoroacetic Acid of PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease.

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 133)Lieferanten
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Hubei xin bonus chemical co. LTD 		86-13657291602
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InvivoChem 		+1-708-310-1919 +1-13798911105
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 masar@topule.com China 8467 58

873436-91-0()Verwandte Suche:

  • 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine
  • 8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9-(3-(isopropylaMino)propyl)-9H-purin-6-aMine
  • PU-H71 Trifluoroacetic Acid
  • 9H-Purine-9-propanamine, 6-amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-
  • NSC 750424
  • 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine PU-H71 Trifluoroacetic Acid
  • PU-H71, >=98%
  • 8-[(6-iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine
  • 9-(3-(Dimethylamino)propyl)-8-((6-iodobenzo[d][1,3]dioxol-5-yl)thio)-9H-purin-6-amine
  • PU-H 71
  • CS-105
  • 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine USP/EP/BP
  • Zelavespib (PU-H71)
  • PU-H71 XHBr
  • PU-H71, 10 mM in DMSO
  • 873436-91-0
  • C18H21IN6O2S
  • API
  • Inhibitors
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