Methyl 1H-pyrrole-3-carboxylate
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- CAS-Nr.
- 2703-17-5
- Englisch Name:
- Methyl 1H-pyrrole-3-carboxylate
- Synonyma:
- Methyl Pyrrole-3-carboxylate;EOS-61577;Methyl 3-pyrrolecarboxylate;Methyl1H-pyrrole-3-carboxylat;3-(Methoxycarbonyl)-1H-pyrrole;Methyl 1H-pyrrole-3-carboxylate;Methyl 1H-pyrrole-3-carboxylate, 95+%;Pyrrole-3-carboxylic acid methyl ester;Methyl 1H-pyrrole-3-carboxylate;1,1-dibromo-2-(chloromethyl)cyclopropane
- CBNumber:
- CB41086094
- Summenformel:
- C6H7NO2
- Molgewicht:
- 125.13
- MOL-Datei:
- 2703-17-5.mol
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Methyl 1H-pyrrole-3-carboxylate Eigenschaften
- Schmelzpunkt:
- 85-89 °C
- Siedepunkt:
- 284℃
- Dichte
- 1.184
- Flammpunkt:
- 126℃
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- 15.42±0.50(Predicted)
- Aggregatzustand
- solid
- Farbe
- Off-white to light yellow
- Wasserl?slichkeit
- Slightly soluble in water.
- InChI
- InChI=1S/C6H7NO2/c1-9-6(8)5-2-3-7-4-5/h2-4,7H,1H3
- InChIKey
- WLBNVSIQCFHAQB-UHFFFAOYSA-N
- SMILES
- N1C=CC(C(OC)=O)=C1
Methyl 1H-pyrrole-3-carboxylate Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Methyl pyrrole-3-carboxylate is used as an organic chemical synthesis intermediate.
Application
A solution of methyl 1H-pyrrole-3-carboxylate (4.48 g, 35.8 mmol) in THF (70 mL) was cooled to -78 °C, N-bromosuccinimide (6.30 g, 35.4 mmol) was added, pyridine (five drops) was added, and the mixture was left standing in a freezer (-20 °C) for 3 days. The reaction mixture was concentrated under reduced pressure. Water was added to the residue, and the mixture was extracted using EtOAc. The extract was washed with brine, dried over Na2SO4, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (hexane-EtOAc = 9/1-1/1) to give Methyl 5-bromo-1H-pyrrole-3-carboxylate (3.59 g, 49percent) as a pale-yellow solid.
Methyl 1H-pyrrole-3-carboxylate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Methyl 1H-pyrrole-3-carboxylate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 161)Lieferanten
2703-17-5()Verwandte Suche:
- 1H-Pyrrole-3-carboxylic acid, methyl ester (9CI)
- Methyl 1H-pyrrole-3-carboxylate
- Methyl1H-pyrrole-3-carboxylat
- Methyl 1H-pyrrole-3-carboxylate, 95+%
- 1H-Pyrrole-3-carboxylic acid methyl ester
- 3-(Methoxycarbonyl)-1H-pyrrole
- Methyl 3-pyrrolecarboxylate
- Pyrrole-3-carboxylic acid methyl ester
- EOS-61577
- 1,1-dibromo-2-(chloromethyl)cyclopropane
- Methyl Pyrrole-3-carboxylate
- methyl 1H-pyrrole-3-carboxylate 1kg 3kg 5kg
- Methyl 1H-pyrrole-3-carboxylate
- 2703-17-5
- Building Blocks
- Heterocyclic Building Blocks
- Pyrroles
- ACIDHALIDE
- 6
