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RO 08-2750

RO 08-2750 Struktur
37854-59-4
CAS-Nr.
37854-59-4
Englisch Name:
RO 08-2750
Synonyma:
RO 08-2750;Ro 08-2750, 10 mM in DMSO;7,10-DIMETHYL-2,4-DIOXOBENZO[G]PTERIDINE-8-CARBALDEHYDE;7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde;2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde;Benzo[g]pteridine-8-carboxaldehyde, 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-;growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro 08-2750,inhibit,Ro 08 2750,factor,MUSASHI
CBNumber:
CB3844689
Summenformel:
C13H10N4O3
Molgewicht:
270.24
MOL-Datei:
37854-59-4.mol

RO 08-2750 Eigenschaften

storage temp. 
Store at -20°C
L?slichkeit
≤2.7mg/ml in DMSO
Aggregatzustand
solid
Farbe
Orange

Sicherheit

RO 08-2750 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ro 08-2750 is a TrkA inhibitor and NGF-induced apoptosis inhibitor.

Biologische Aktivit?t

Non-peptide inhibitor of NGF that binds the NGF dimer (K D ~ 1 μ M) possibly causing a conformational change. Inhibits binding selectively to p75 NTR at submicromolar concentrations and to both p75 NTR and TrkA at higher concentrations (> 5 μ M). Prevents NGF-induced apoptosis in SK-N-MC cells.

RO 08-2750 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RO 08-2750 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 44)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
ivan@atkchemical.com China 32965 60
Changzhou PBpharmaceutical R&D Co.,Ltd 		0519-83990708
info@pbpharm.com CHINA 498 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
InvivoChem 		+1-708-310-1919 +1-13798911105
 sales@invivochem.cn United States 6391 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185
 sales-cpd@caerulumpharma.com China 3466 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Shanghai Shanyuan pharmaceutical technology co., LTD 021-31761238 13167072949
 3146446224@qq.com China 1636 55
Changzhou PBpharmaceutical R&D Co.,Ltd 0519-83990708
lxy2046@yeah.net China 476 55

37854-59-4()Verwandte Suche:

  • 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde
  • RO 08-2750
  • 7,10-DIMETHYL-2,4-DIOXOBENZO[G]PTERIDINE-8-CARBALDEHYDE
  • Benzo[g]pteridine-8-carboxaldehyde, 2,3,4,10-tetrahydro-7,10-dimethyl-2,4-dioxo-
  • growth,MSI,Ro 082750,p75NTR,TRKA,RNA-binding,Nerve,NGF,Inhibitor,leukemia,Apoptosis,AML,Ro 08-2750,inhibit,Ro 08 2750,factor,MUSASHI
  • 7,10-dimethyl-2,4-dioxo-2,3,4,10-tetrahydrobenzo[g]pteridine-8-carbaldehyde
  • Ro 08-2750, 10 mM in DMSO
  • 37854-59-4
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