COX-1 (ovine) Inhibitor Screening Assay Kit Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
COX-
1 and COX-
2 catalyze the production of the prostaglandin (PG) and thromboxane precursor PGH
2. COX-
2 is primarily responsible for the biosynthesis of PGs under acute inflammatory conditions. The COX-
1 (ovine) Inhibitor Screening Assay measures PGF
2α that is produced by SnCl
2 reduction of COX-
1-
derived PGH
2. PGF
2α is quantified
via enzyme immunoassay (EIA) using a broadly specific antiserum that binds to all the major PG compounds. This assay includes ovine COX-
1 and is an excellent tool which can be used for general inhibitor screening, or to eliminate false positive leads generated by less specific methods.
COX-1 (ovine) Inhibitor Screening Assay Kit Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte