Schisandrin
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Schisandrin Eigenschaften
- Schmelzpunkt:
- 128.5°C
- Siedepunkt:
- 466.17°C (rough estimate)
- Dichte
- 1.1480 (rough estimate)
- Brechungsindex
- 1.5800 (estimate)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥13mg/mL
- Aggregatzustand
- powder
- pka
- 14.58±0.40(Predicted)
- Farbe
- white to beige
- Optische Aktivit?t
- [α]/D 75 to 95°, c = 1 in methanol
- InChIKey
- YEFOAORQXAOVJQ-UHFFFAOYSA-N
- LogP
- 3.153 (est)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher | Xn,N | ||
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R-S?tze: | 22-50/53 | ||
S-S?tze: | 60-61 | ||
RIDADR | UN 3077 9 / PGIII | ||
WGK Germany | 3 | ||
HS Code | 29093090 |
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Alarmwort | Warnung | |||||||||||||||||||||
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Sicherheit |
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Schisandrin Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Schizandrin is a dibenzocyclooctadiene lignan and a major component of S. chinensis and has diverse biological activities. It induces cell cycle arrest at the G0/G1 phase and inhibits growth of T47D and MDA-MB-231 breast cancer cells when used at a concentration of 100 μM. Schizandrin (10 and 100 μM) prevents glutamate-induced cytotoxicity, inhibits production of nitric oxide (NO) and reactive oxygen species (ROS), and preserves the mitochondrial membrane potential in isolated rat cortical cells. It reduces apoptosis induced by cisplatin in HK-2 human kidney cells. In vivo, schizandrin (1 and 10 mg/kg, p.o.) reverses scopolamine-induced impairment of spatial memory and the passive avoidance response in rats. It enhances oxotremorine-induced tremors in mice. Schizandrin (10 mg/kg) reduces serum levels of IgE, IgG1, IL-4, and IFN-γ in an ovalbumin-sensitized mouse model of allergy.Verwenden
Schizandrin may be used in oxidative stress-related cell signaling studies.Application
Schizandrin is a natural compound that belongs to the group of schisandrins. Schizandrins are a class of compounds with biochemical properties and biological activities, such as anti-inflammatory, antioxidant, and anti-cancer effects. This compound has been shown to have pro-apoptotic properties in a model system. It has also demonstrated the ability to inhibit influenza A virus replication in vitro and protect mice against Listeria monocytogenes infection. It can be used as an inhibitor of gsh-px activity in myocardial infarcts.Biochem/physiol Actions
Schizandrin is a natural product with several biological properties involved with antioxidant and anti-inflammatory activities. It reduces the formation of ROS, inhibits the mitochondrial pathway of the apoptotic process and oxidative stress. Schizandrin has been reported to have hepatoprotective, antitumor, antiviral, and antiamnesic effects, and has neuroprotective activity against glutamate induced neurotoxicity.Schisandrin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Schisandrin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 301)Lieferanten
Firmenname | Telefon | Land | Produktkatalog | Edge Rate | |
---|---|---|---|---|---|
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3772 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21634 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29879 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 1169 | 58 |
NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 |
sale02@cqherb.com | CHINA | 376 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
7432-28-2()Verwandte Suche:
Schisandrin A
4-Methoxybenzylalkohol
Dimethylphthalat
Dimethylfumarat
Nortropine
Dimethyl ether
Dimethyl sebacate
Dimethylcarbonat
N,N-Dimethylformamid
SCHIZANDRIN B
Dimethylsulfoxid
Ethan
(R*,S*)-4,4'-(2,3-Dimethylbutan-1,4-diyl)bisbrenzcatechin
Biphenyl-2,2'-diol
3,4-Dimethoxyphenethylalkohol
Biphenyl-4,4'-diol
γ-Schisandrin
SCHISANDROL B (GOMISIN A)(P)
- Schisandrin,Schizandrin
- chisandrin 5,6,7,8-Tetrahydro-6,7-dimethyl-1,2 3,10,11,12-hexamethoxydibenzo[a,c]cycloocten-6-ol
- Schizandrin, >=98%
- SCHISANDRIN
- WUWEIZI ALCOHOL A
- SCHISANDRIN (SCHISANDROL A)
- Schizandrin std.
- Schisandrin(Schizandrol A)
- Schisadrol A
- dibenzo(a,c)cycloocten-6-ol,5,6,7,8-tetrahydro-6,7-dimethyl-1,23,10,11,12-hex
- schizandra
- 5,6,7,8-Tetrahydro-6,7-dimethyl-1,2 3,10,11,12-hexamethoxydibenzo[a,c]cycloocten-6-ol
- (+)-Schizandrin Schisandrin Schisandrine Wuweizi alcohol A Schizandrin
- 1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-,(6S,7S
- 12aR)-
- Dibenzo[a,c]cycloocten-6-ol, 5,6,7,8-tetrahydro-
- 5,6,7,8-Tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-6-ol
- Schizandrin, 98%, from Schisandra chinensis (Turcz.) Baill.
- Schisandrae Berry Extract
- Schisandrol A 7432-28-2
- Schisandrin (Schizandrol
- Dibenzo[a,c]cycloocten-6-ol, 5,6,7,8-tetrahydro-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-, (6S,7S,12aR)-
- hot selling Schisandra Berries P.E
- DeoxyschizandrinSchisandra chinensis extract
- (6S,7S,12aR)-1,2,3,10,11,12-Hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulen-6-ol
- SCHIZANDROL
- SCHIZANDROL A
- SCHIZANDRIN
- SCHISANDROL A
- Schisandrol
- Schisandrin methyl
- Schisandrol A structure
- Abametapir Impurity 29
- 7432-28-2
- C24H32O7
- Inhibitors
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Miscellaneous Natural Products
- Natural Plant Extract
- chemical reagent
- pharmaceutical intermediate