Monoclonal Anti-CBLL1, (N-terminal) antibody produced in mouse Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Monoclonal Anti-CBLL1, (N-terminal) antibody produced in mouse is suitable for indirect ELISA and western blot analysis.
Allgemeine Beschreibung
Epithelial cell cadherin (CDH1; MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A; MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM
Biochem/physiol Actions
CBLL1 (Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase) is an E-cadherin binding protein involved in the ubiquitination of E-cadherin and regulation of E-cadherin complex endocytosis. During ubiquitination, it directly binds to the cytoplasmic domain of E-cadherin. It has been reported in a study that CBLL1 may play a role in neuronal apoptosis and in LPS (Lipopolysaccharide) administration. CBLL1 have also been predicted as a regulator of cell proliferation.
Monoclonal Anti-CBLL1, (N-terminal) antibody produced in mouse Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
